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OATech+ Network: Funding Review Leanne Sawle

OATech+ Network: Funding Review Leanne Sawle. Budget Budget for activities and projects £741,331 £238,779 consumables £227,552 travel £275,000 research pot. General Spending Spent Pending £69,040.07 £4,568.86. To develop tools for patient stratification in OA

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OATech+ Network: Funding Review Leanne Sawle

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  1. OATech+ Network: Funding Review Leanne Sawle

  2. Budget Budget for activities and projects £741,331 £238,779 consumables £227,552 travel £275,000 research pot

  3. General Spending Spent Pending £69,040.07 £4,568.86

  4. To develop tools for patient stratification in OA To identify the characteristics of ‘pain’ and ‘structural damage’ characteristics in OA Nidhi Sofat (Clinical Applications), St George’s Developing tools for Patient Stratification in Osteoarthritis £86,774 (1/10/18 – 30/9/19) Commitments – Network projects (80% fEC) Mark Elliott (Data and Data Analytics), Warwick OA Datasets Scoping Project £62,273 (28/1/19- 27/9/19) Feasibility of creating an OA Datasets resource Alan Turing Institute call for data sets and application challenges (clinical gait analysis)

  5. Commitments – Network projects (80% fEC) Richard Jones (Lifestyle Interventions), Salford (also involving David Hamilton, Edinburgh) The role of technology and lifestyle interventions in osteoarthritis £46,233 Systematic review

  6. Commitments – Network projects (80% fEC) Debbie Mason + Alison McGregor (high-level evidence and impact), Cardiff Systematic review to define the higher level evidence in osteoarthritis research that can be used to develop an impact toolkit £57,015 (1/1/19-30/6/19) Imaging group /Cathy Holt, Cardiff Development of MRI protocols to create 3D computer models and structural imaging for model-based image registration. Development of in vivo dynamic biplane X-ray protocols£60,585 (1/7/19)

  7. Developing a cartilage phantom for assessing cartilage composition using quantitative MR sequences Commitments – Network projects (Sandpit awards) David Williams, Cardiff (involving H. Markides, Birmingham) Development of a quantitative MRI phantom for knee tissue £19,086 (1/7/19 - 30/6/20) Debbie Mason and David Hamilton (Cardiff and Edinburgh) We don’t care how much it hurts (but we do care about nocioception) £18,750 (1/8/19 - 31/1/20) Wearable sensors as objective measures of nocioception

  8. 3 x 3K awards made Commitments – Network activities Awards of up to 10K to be announced

  9. Commitments – Network activities a) Importance of activity measurement pre‐post TKR b) Assessing quality of movement? c) Priorities for technological advancements measurement of activity? d) Opportunities for multi‐centre research PDRA to start 1/7/19

  10. Commitments – Network activities Identify key dissemination routes Subject-specific modelling of the human knee to chose the best treatment among different types (total knee replacement, condyle resurfacing, osteochondral plugs) Clinicians can pose “real world” problems

  11. Commitments – Network activities Public engagement pots of money 50K award for gathering preliminary data on multi-scale modelling of primary OA including pain

  12. Commitments – General

  13. Commitments – General

  14. Final Review (May 2019)

  15. Data repository Network legacy Data sets are being gathered (750 volunteers) Future Plans

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