An introduction to MedicinesComplete

1. An introduction to MedicinesComplete

2. What is MedicinesComplete? • MedicinesComplete is an online subscription service • Providing online access to world leading drug and healthcare resources • Updated regularly by Pharmaceutical Press, the publishing division of the Royal Pharmaceutical Society • Contains products from our publishing partners: • British Medical Association • American Pharmacists Association • Royal Pharmaceutical Society • American Society of Health-System Pharmacists • To visit our site, go to http://www.MedicinesComplete.com

4. The new MedicinesComplete v3.0 • Improved navigation to preparations, interactions, drug monographs, adverse effects or treatment and so on • Organisational branding • Additional login mechanisms, including the ability to stay logged into your personal account • Open URL enabled reference links • New enhanced navigation within a document • Improved global search • Improved workflow integration • Term recognition and weighting provides intelligent and relevant results • Specialty limits applied to the global search provides focus across a broad set of resources • Intelligent guidance for unrecognised search terms, ensuring zero results are reduced

5. Subscriber welcome page

6. Multi method login

7. Global search result

8. Result filter tabs Selected resource search results

9. Monograph

10. In document navigation

11. Open URL enabled

12. The Facts • More than 30,000 drug, poison, interaction and herbal monographs • The latest advice on prescribing, dispensing and administering drugs and medicines • The combined knowledge of hundreds of leading experts, scientists and researchers • Over 100,000 references to original research, scientific papers, reports and cases studies – PubMed links • Up-to-date guidance on disease treatments, disease management and therapeutics • Complete international coverage

13. Features • Quick easy-to-use ‘global’ search across all resources • Intuitive interface with a new clean look and layout • Unique mix of world leading drug information resources • New search filtering allows for quick access to key information • Trusted, unbiased, global, clinically proven information • Regular content updates • Flexible access options such as IP address authentication, Athens and Shibboleth • Open url reference linking

14. Benefits • Flexible choice of product tailored to your requirements • Price structure to suit your budget • Training can be provided by our sales team plus online PowerPoint and Flash demo’s • Usage statistics can be provided including search trends • Global company wide availability to comprehensive and reliable drug information

15. The Resources • AHFS Drug Information • Published by the American Society of Health-System Pharmacists • Covers drug interactions; adverse reactions; toxicity; therapeutic perspective; specific dosage and administration information; preparations, chemistry, stability; pharmacology and pharmacokinetics; contraindications; and more. • Every year an average of over 60% of AHFS content is revised • Contains over 1,200 monographs • Over 40,000 represented medicines and over 100,000 drug products • Over 70,000 uniquely cited references • Expert advice and peer reviewed • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/ahfs/current/

16. The Resources • British National Formulary • Published jointly by the British Medical Association and the Royal Pharmaceutical Society of Great Britain, • The BNF details medicines prescribed in the UK, • Covers uses, cautions, contra-indications, side-effects, dosage and relative costs • Best practice, legal and professional guidelines relating to the use of medicines • Designed for rapid reference, • Advice on prescribing, dispensing and administering medicines • The BNF is used 600,000 a day, 3 million times per week • The BNF 1 had 376 pages, the BNF 56 has 976 pages • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/bnf/current/

17. The Resources • BNF for Children • Published jointly by the BMA, RPSGB, the Royal College of Paediatrics and Child Health, and the Neonatal and Paediatric Pharmacists Group, • Prescribing, dispensing, monitoring, and administration of medicines to children. • Encourages the safe, effective, and appropriate use of medicines for the management of childhood conditions. • Validated against emerging evidence, best practice guidelines, and advice from a network of clinical experts. • The text is published under the authority of a Paediatric Formulary Committee. • Includes authoritative advice on licensed as well as unlicensed and “off-label” use of medicines for children from birth up to the age of 18 years. • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/bnfc/current/

18. The Resources • Clarke’s Analysis of Drugs and Poisons • For use primarily by scientists faced with identifying and quantifying drugs and poisons in body fluids, tissue samples and pharmaceutical and industrial products. • Over 1700 drug and poison monographs • Details physical properties, analytical methods, pharmacokinetic data, ultraviolet, infra-red and mass spectra, and therapeutic and toxicity data of drugs and poisons • 31 sections cover all practice areas and analytical procedures • International in scope and coverage • Represents the combined knowledge of the analytical and forensic toxicology community no other drug analysis reference has the depth and breadth • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/clarke/current/

19. The Resources • Dietary Supplements • Provides up-to-date information on safety and efficacy of dietary supplements. • Includes the latest findings on the most commonly used dietary supplements • Over 100 comprehensively referenced monographs • Regulations relating to dietary supplements in UK, Europe and the USA • Useful appendices including a summary of interactions with conventional medicines • Recently added monographs include; Collagen, Hyaluronic acid, Multivitamins & Pumpkin seed • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/diet/current/

20. The Resources • Drug Administration by Enteral Feeding Tubes • A practical guide to the safe administration of medicines via enteral feeding tubes • Ten chapters provide the background knowledge to inform clinical decisions • Accompanying 344 monographs • Guidance on the safe administration of specific drugs and formulations • Contents include: types of enteral feeding tubes, tube flushing, restoring and maintaining patency, drug therapy review, medication formulation choice, unlicensed medication use, health and safety and interactions. • For further information please refer to the resource fact sheet or visit https://www.medicinescomplete.com/mc/tubes/current

21. The Resources • Handbook on Injectable Drugs • The ultimate authority on compatibility and stability of injectable drugs. • 372 drug monographs • 2,623 references • Make accurate assessments of the compatibility of various solutions and additives with a particular drug • FAQ’s on preparation, storing and administration of injectable drugs • Includes AHFS classification numbers • Including common sizes, strengths, volumes, forms, pH, osmotic value, etc • Storage requirements and general stability information, • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/hid/current/

22. The Resources • Herbal Medicines • Invaluable online resource for evidence-based information on herbal medicines • Addresses the issues of quality, safety and efficacy • Scientifically rigorous, impartial, evidence based, information on medicinal herbs • Over 150 monographs, comprehensively referenced • Safety and interactions of a herbal medicine • Clinical indication and dosage • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/herbals/current/

23. The Resources • Martindale: The Complete Drug Reference • Martindale: The complete drug reference - trusted source for medicines information for over 120 years. • Worldwide coverage - unrivalled global focus • Comprehensive, unbiased, reliable and evaluated • Martindale forms the backbone of MedicinesComplete. • Regularly updated • Synopses of treatments for more than 660 diseases • Over 6,300 Drug Monographs, 149,000 Preparations, 40,700 References and 14,700 Manufacturers’ Details • Includes herbals, diagnostic agents, radiopharmaceuticals, pharmaceutical excipients, toxins, and poisons as well as drugs and medicines • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/martindale/current/

24. The Resources • Pharmaceutical Excipients • Comprehensive guide to the uses, properties and safety of pharmaceutical excipients. • Internationally acclaimed and one of the most authoritative • Physical properties of individual excipients with comparative data on different grades from the same or different suppliers • Over 300 fully referenced excipient monographs • Ideal for those involved with the development, production, control and regulation of pharmaceutical preparations, or production of confectionery, cosmetics and food products • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/excipients/current/

25. The Resources • Rules and Guidance for Pharmaceutical Manufactures and Distributors • Essential reference for all involved in the manufacture or distribution of medicines in Europe. • Collates in one convenient and authoritative source European and UK guidance documents and information on legislation relating to the manufacture and distribution of medicines for human use. • Bring together the main pharmaceutical regulations, directives and guidance for manufacturers and wholesalers • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/orange/current/

26. The Resources • Stability-Indicating HPLC Methods for Drug Analysis • The only compilation of stability-indicating high-performance liquid chromatographic (HPLC) analytical methods • Analysts can now avoid the tedium of lengthy literature searches • A more in-depth, extensive description of the HPLC analysis presented in the literature • Information on 572 different drug entities presented in structured monographs containing 30 elements • 1,028 stability-indicating HPLC analytical methods • Unique in focusing on stability-indicating HPLC methods • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/hplc/current/

27. The Resources • Stockley’s Drug Interactions • The world’s most comprehensive and authoritative international reference source on drug interactions • Quick and easy access to clinically relevant, evaluated, and evidence-based online information on interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and drugs of abuse. • Over 14,000 drug interactions in 2,800 Monographs • Includes over 17,600 references • International coverage • Ability to enter up to 12 drugs at a time • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/stockley/current/

28. The Resources • Stockley’s Interaction Alerts • Stockley's Interaction Alerts is based on the full text of Stockley's Drug Interactions. • The wealth of information has been reduced into succinct two-part messages to provide a brief overview of the evidence behind the interaction • Allows instant review of possible drug interactions • Covers over 40,000 drug–drug, drug–alcohol or drug–food pairs • Rating system easily identifies the depth of background information and gauges the potential severity of each interaction • Links to full text of Stockley's Drug Interactions • Invaluable and up-to-date, clinical decision making tool • International coverage • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/alerts/current/

29. The Resources • The Merck Index • World renowned reference source for chemical, pharmaceutical and biomedical information • Over 10,000 monographs • Critically evaluated, peer-reviewed, and authoritative information on compounds of significance in research, commerce, and environmental impact. • Monographs provide descriptions of more than 18,000 substances across multiple scientific disciplines including: • Drugs for humans and animals • Organic chemicals used in research and manufacturing • Plants and traditional medicines • Natural products, toxins and biologicals • Agricultural chemicals, pesticides, and herbicides • Food additives and nutritional supplements • Fragrances, fl avours, cosmetics, dyes, stains and colours • For further information please refer to the resource fact sheet or visit http://www.medicinescomplete.com/mc/merck/current

30. Publishing Partners • American Pharmacists Association (APA) • American Society of Health-System Pharmacists (ASHP) • British Medical Association (BMA) • Royal Pharmaceutical Society of Great Britain (RPS) • Royal College of Paediatrics and Child Health • Neonatal and Paediatric Pharmacists Group