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Explore how crystal structures of PTP domains (PTP1B, RPTPa, RPTPm, LAR, SHP1, SHP2) exhibit a conserved fold and Ca-backbone trace. Learn more at ptp.cshl.edu & science.novonordisk.com/ptp. (Maximum 500 characters)
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N-terminal Central a3-helix Crystal structures of PTP domains show a conserved fold and consistent Ca-backbone trace Superimposition of PTP1B (magenta), RPTPa (gray), RPTPm (red), LAR (blue), SHP1 (green) and SHP2 (yellow). http;//ptp.cshl.edu & http://science.novonordisk.com/ptp Andersen et al Mol. Cell. Biol. 2001