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MLAB 2401: Clinical Chemistry

2. Introduction . When evaluating laboratory results, how do we determine that is normal or acceptable? In other words: What is

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MLAB 2401: Clinical Chemistry

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    1. 1 MLAB 2401: Clinical Chemistry Quality Control, Quality Assessment and Statistics

    2. 2 Introduction When evaluating laboratory results, how do we determine that is normal or acceptable? In other words: What is normal or OK? When does a laboratory test result become weird or abnormal ? When do be become uncomfortable with a result? At some point we have to draw a line in the sand on this side of the line youre normal on the other side of the line youre abnormal. Where and how do we draw the line ? Answer: Statistics are used to determine the lines of normal and acceptable.

    3. 3 Introduction Statistics is used to draw lines in the sand for patient specimens, control specimens and calibrators If the results are normal we re comfortable about them and dont worry But if theyre abnormal, were uncomfortable and we fear that there is something wrong with the patient or that something is wrong with the test procedure

    4. 4 Statistical Concepts Statistics is a (science of )branch of mathematics that collects, analyzes, summarizes and presents information about observations. In the clinical lab, these observations are usually numerical test results A statistical analysis of lab test data can help us to define normal ranges for patients ( normal and abnormal ) and acceptable ranges for control specimens ( in and out of control )

    5. 5 Statistical Formulas Standard Deviation (SD) Is a mathematical expression of the dispersion of a group of data.

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