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The Top Five Science Drivers for Quantum Limited Detectors: Medical and Biology

The Top Five Science Drivers for Quantum Limited Detectors: Medical and Biology. Real time diagnostic information Confocal microscopy (Damage to tissue) Molecular imaging (luminescence, fluorescence…) Radiology and CT – volumetric imaging, dyamic imaging in particular NIRS

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The Top Five Science Drivers for Quantum Limited Detectors: Medical and Biology

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  1. The Top Five Science Drivers for Quantum Limited Detectors: Medical and Biology Real time diagnostic information Confocal microscopy (Damage to tissue) Molecular imaging (luminescence, fluorescence…) Radiology and CT – volumetric imaging, dyamic imaging in particular NIRS Gamma-ray modalities (PET, SPECT…) Safety THz imaging??????? 1

  2. Top Detector Characteristics

  3. The Most Promising Detector Technologies for: Medical & Biology Photon counting Very large area (tiling, …) Avalanche (APDs, EM CCDs) 3D detector/circuit integration 5

  4. Hurdles for the Most Promising Detector Technologies for: Medical & Biology 6

  5. Detector R&D Roadmap for: Astrophysics GM-APD demonstrate ~64x64 diode/ROIC array at 150 K design megapixel array and demonstrate at telescope ???? SPNW Materials demonstrate low dark curent mid-wave MCT ??? ??? ??? ??? 7

  6. Funding Possibilities: Medical & Biology NIH – NIBIB (esp. med. Imaging inst.) NSF Homeland Security, DOD (inspection) HHMI 8

  7. The Top Detector Characteristics for:Medical and Biology zero read noise in-pixel wavelength discrimination (energy discrimination for radiology) larger formats (>10K x 10K)‏ lower power, higher temp. operation Lower cost operation (e.g. standardized ASIC, easier than SIDECAR)‏ high dynamic range: 1 - 1E7 photons high speed capabilites, yet retain low noise ??? 9

  8. Reference Chart: Key Detector Characteristics Homeland Safety Biomedical Imaging Earth System Science Defense Quantum-Limited Imaging Detector Read Noise Dark Current QE λ λ/Δλ Δt P

  9. Detector Performance Requirements for: Astrophysics 11

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