1 / 32

Rheumatoid Arthritis and Systemic Lupus Erythematosus

Rheumatoid Arthritis and Systemic Lupus Erythematosus. RA - Predisposing Factors. Gender. Infection. Genetic. Hormonal. RA. SLE - Predisposing Factors. Gender. Race. Genetic. Toxins UV light. SLE. Pathophysiology - RA. Antigenic Stimulus (virus?). IGg formed.

velma-alexander
Télécharger la présentation

Rheumatoid Arthritis and Systemic Lupus Erythematosus

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Rheumatoid Arthritis and Systemic Lupus Erythematosus

  2. RA - Predisposing Factors Gender Infection Genetic Hormonal RA

  3. SLE - Predisposing Factors Gender Race Genetic Toxins UV light SLE

  4. Pathophysiology - RA Antigenic Stimulus (virus?) IGg formed Rheumatoid Factor (RF) Autoantibody IGg + RF = Immune Complexes Deposited in joints, vessels and pleura

  5. RA - Pathophysiology Microvascularinjury = synovial inflammation Pannus formation = invades joint and bone Fibrous tissue replaces pannus= deformity and dysfunction Calcification + ankylosis = immobility

  6. SLE - Pathophysiology or

  7. SLE - Pathophysiology Antigen - Antibody Complex Complement Activation Immune Complex Buildup = Lupus Vasculitis Ischemia

  8. SLE - Pathophysiology ISCHEMIA Thickened lining Fibrinoid degeneration Thrombus

  9. Complications of RA

  10. Complications of RA -Cysts

  11. Complications of RA - Cysts - Infection

  12. Complications of RA - Cysts - Infection - Osteoporosis

  13. Complications of RA - Cysts - Infection - Osteoporosis - Amyloidosis

  14. Complications of RA - Cysts - Infection - Osteoporosis - Amyloidosis - Spinal Cord Compression

  15. Complications of SLE INFECTION

  16. Clinical Manifestations of RA and SLE

  17. DiagnosticTests

  18. Diagnostic Tests - RA - ESR - Elevated in 85% - Used to monitor response to TX - RF - Greater than 1:160 in 80% - WBC - Greater than 30,000 in synovial fluid

  19. Diagnostic Tests - RA - Synovial Fluid - Increased volume and turbidity - Decreased viscosity - X-ray - Early - Bone Demineralization - Soft tissue swelling - Late - Narrowed joint space - Erosion - Deformity

  20. Diagnostic Tests - SLE - ESR - Increased - Gamma Globulin - Increased - Hct - WBC - Platelets Decreased

  21. Diagnostic Tests - SLE - EKG - X-ray - Pericarditis - Pleural effusion

  22. Diagnostic Tests - SLE - Antinuclear Antibody (ANA) - Present in 99% of cases - Not specific for SLE - RPR - False positives - UA - Cellular casts - Proteinuria

  23. Diet Therapy RA and SLE Depression Steroids H20 Retention

  24. LIFESTYLE INTERVENTIONS

  25. Lifestyle Interventions - RA PAIN !!!!! - Thermal Treatment - Heat up to 20 minutes - Cold up to 15 minutes - Decrease stress to joints (modify tasks) - Pain meds before activities

  26. Lifestyle Interventions - RA MOBILITY - ROM - in water and out - Moist heat - Rest joints - splints and modify tasks - More strenuous activities later

  27. Lifestyle Interventions - RA INCREASE ENERGY - Schedule and space activities - Rest periods - Regular exercise to tolerance - Energy conservation - Joint protective devices

  28. Lifestyle Interventions - RA SELF-CARE DEFICIT - Assistive devices - Sequence activities

  29. Lifestyle Interventions - SLE EFFICIENT ENERGY EXPENDITURE - Spacing - Scheduling - Sequencing

  30. Lifestyle Interventions - SLE SKIN INTEGRITY - Mild soap and water - Avoid sun - Only Rx. skin lotions

  31. Lifestyle Interventions - SLE INCREASE ACTIVITY - Pacing - Relaxation techniques - Pain management - Recreational activities

  32. Lifestyle Interventions - SLE ADEQUATE NUTRITION - Manage depression - Food preferences - Small frequent meals - Monitor lab values

More Related