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Impact of Colorectal Cancer Screening: Glasgow Study Initial Findings

Collaborative research by Glasgow University explores impact on high-risk features, disease stage, tumor characteristics, and systemic inflammatory response in colorectal cancer patients from screening vs. non-screening cohorts. Informative study results and conclusions provided.

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Impact of Colorectal Cancer Screening: Glasgow Study Initial Findings

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  1. The Impact of Colorectal Cancer Screening – Initial Results Mr Michael Proctor, MD Research Fellow, Academic Unit of Surgery, Royal Infirmary, University of Glasgow.

  2. The Impact of Colorectal Cancer Screening • Collaboration • Glasgow University Department of Surgery, Royal Infirmary • Department of Clinical Pathology, Royal Infirmary • Public Health Screening Unit, Greater Glasgow and Clyde • Aims to investigate the impact on high risk features • Disease stage1 • Tumour pathological characteristics 2 • Host systemic inflammatory response3 • Patients • Greater Glasgow and Clyde Bowel Screening detected cancers (SD) • Glasgow Royal Infirmary non-screen detected cancer cohort (NSD) (1) Dukes , J Path 1932. (2) Petersen et al., Gut 2002. (3) Proctor et al., BJC 2011.

  3. Screen Detected Cancer Stage National Cancer Intelligence Network, 2009.

  4. Patient Characteristics

  5. Tumour Site Right Sided SD - 30% NSD - 40% Left Sided SD - 48% NSD - 24% Rectal SD - 22% NSD - 36%

  6. Tumour and Nodal Stage P <0.001 P=0.414

  7. High Risk Factors

  8. Host Systemic Inflammatory Response

  9. Conclusion • Bowel screening results in improved host and tumour related prognostic factors when compared to a non-screen detected cohort.

  10. Questions?

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