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This research investigates the interactions between Bcl-xS and Bcl-xL in the context of pre-mRNA lariats. We delve into how these proteins influence the splicing process, focusing on their role in regulating cell survival and apoptosis. Using a collection of molecular data and experimental results, we explore the mechanisms behind the formation and processing of lariat structures in pre-mRNA. This study provides insights into the regulatory functions of Bcl proteins and their potential impact on gene expression.
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U1-2’-O-Me + + + + M4-25D bcl-xS lariats bcl-xL lariats pre-mRNA 1 2 3 4 5 6 7 8 xL /xS 6.32.02.30.8 0.7 2.9 1.0 2.7