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Growth and development

Growth and development. Samir Najjar M.D Professor, Department of Pediatrics. Stages of growth and development. Intrauterine Infancy Childhood Adolescence Adulthood. Intrauterine Growth. Greatest length velocity at mid fetal life Development of adipose tissue at 7 months

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Growth and development

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  1. Growth and development Samir Najjar M.D Professor, Department of Pediatrics

  2. Stages of growth and development • Intrauterine • Infancy • Childhood • Adolescence • Adulthood

  3. Intrauterine Growth • Greatest length velocity at mid fetal life • Development of adipose tissue at 7 months • weight doubles in the last 2 months • Weight loss beyond 40 weeks

  4. Constrains on intrauterine growth • Uterine size • Placenta • Size of the mother

  5. Infancy • The era of changing growth rate

  6. Childhood • The era of stable growth rate

  7. Adolescence • The era of sex hormone induced shifting growth

  8. What is short stature

  9. CLASSIFICATION OF SHORT STATURE SHORT STATURE PATHOLOGIC PROPORTIONATE • PRENATAL • Intrauterine growth retardation (IUGR) • Placental diseases • Infections • Teratogens • Dysmorphic syndromes • Chromosomal disorders • NORMAL VARIANTS • Familiar short stature • Constitutional growth delay • DISPROPORTIONATE • Skeletal dysplasia • Rickets • POSTNATAL • Malnutrition • Chronic diseases • Gastrointestinal • Cardiopulmonary • Infections • Renal • Hematologic • Drugs • Psychosocial dwarfism • Endocrine disorder

  10. CLASSIFICATION OF SHORT STATURE SHORT STATURE PATHOLOGIC PROPORTIONATE • PRENATAL • Intrauterine growth retardation (IUGR) • Placental diseases • Infections • Teratogens • Dysmorphic syndromes • Chromosomal disorders • NORMAL VARIANTS • Familiar short stature • Constitutional growth delay • DISPROPORTIONATE • Skeletal dysplasia • Rickets • POSTNATAL • Malnutrition • Chronic diseases • Gastrointestinal • Cardiopulmonary • Infections • Renal • Hematologic • Drugs • Psychosocial dwarfism • Endocrine disorder

  11. CLASSIFICATION OF SHORT STATURE SHORT STATURE PATHOLOGIC PROPORTIONATE • PRENATAL • Intrauterine growth retardation (IUGR) • Placental diseases • Infections • Teratogens • Dysmorphic syndromes • Chromosomal disorders • NORMAL VARIANTS • Familiar short stature • Constitutional growth delay • DISPROPORTIONATE • Skeletal dysplasia • Rickets • POSTNATAL • Malnutrition • Chronic diseases • Gastrointestinal • Cardiopulmonary • Infections • Renal • Hematologic • Drugs • Psychosocial dwarfism • Endocrine disorder

  12. CLASSIFICATION OF SHORT STATURE SHORT STATURE PATHOLOGIC PROPORTIONATE • PRENATAL • Intrauterine growth retardation (IUGR) • Placental diseases • Infections • Teratogens • Dysmorphic syndromes • Chromosomal disorders • NORMAL VARIANTS • Familiar short stature • Constitutional growth delay • DISPROPORTIONATE • Skeletal dysplasia • Rickets • POSTNATAL • Malnutrition • Chronic diseases • Gastrointestinal • Cardiopulmonary • Infections • Renal • Hematologic • Drugs • Psychosocial dwarfism • Endocrine disorder

  13. CLASSIFICATION OF SHORT STATURE SHORT STATURE PATHOLOGIC PROPORTIONATE • PRENATAL • Intrauterine growth retardation (IUGR) • Placental diseases • Infections • Teratogens • Dysmorphic syndromes • Chromosomal disorders • NORMAL VARIANTS • Familiar short stature • Constitutional growth delay • DISPROPORTIONATE • Skeletal dysplasia • Rickets • POSTNATAL • Malnutrition • Chronic diseases • Gastrointestinal • Cardiopulmonary • Infections • Renal • Hematologic • Drugs • Psychosocial dwarfism • Endocrine disorder

  14. Accepted indications for GH therapy • Childhood GH deficiency • Growth failure associated with chronic renal insufficiency • Turner syndrome • IUGR • Adults with GH deficiency

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