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Ultra-Short Cold Ischemia: Key to Avoid Ischemic Cholangiopathy in DCD-LT?

Explore the experience of DCD-LT with short cold ischemia time & no age limit, minimizing graft loss in ischemic cholangiopathy. Report on 70 consecutive cases in a 10-year retrospective study.

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Ultra-Short Cold Ischemia: Key to Avoid Ischemic Cholangiopathy in DCD-LT?

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  1. IS ULTRA-SHORT COLD ISCHEMIA THE KEY TO ISCHEMIC CHOLANGIOPATHY AVOIDANCE IN DCD-LT? O Detry, A Deroover, S Cheham, H Ledinh, C Coimbra, E Decker, L Kohnen, MF Hans, J Joris, S Lauwick, A Kaba, J Delwaide, M Meurisse, P Honoré University of Liege, CHU Liege, Belgium Donation after circulatorydeath (DCD) livertransplantation (LT) hasbeenintroducedtopartiallyovercometheorgandonorshortage DCD LT haslower graft survival due toincreaseratesofprimary non-functionand graft loss due toischemiccholangiopathywithdifficulttotreat non-anastomoticbiliarystrictures Aim: Report theauthors‘ experience in DCD-LT, with a shortcoldischemia time andwithoutupperlimitagecriteria • Retrospective 10 yearsmonocentricexperience • Center-orientedallocationwithinthe Eurotransplant organisation • Noupperlimit DCD donoragecriteria • 70 consecutive DCD-LT • DCD in OR, withheparinanddonorcomforttherapy • Death on circulatorycriteria • 5 min no-touchperiod

  2. DCD maybe a valuablesourceoflivergrafts • DWIT < 30 min & CIT < 5 hoursmayleadto a low rate of graft loss due to PNF and/orischemiccholangiopathy • With DWIT < 30 min & CIT < 5 hours, DCD donors > 60 yearssouldbeconsideredtoreallyincreasethecadavericdonorpool

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