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IS ULTRA-SHORT COLD ISCHEMIA THE KEY TO ISCHEMIC CHOLANGIOPATHY AVOIDANCE IN DCD-LT?. O Detry, A Deroover , S Cheham , H Ledinh , C Coimbra, E Decker, L Kohnen , MF Hans, J Joris , S Lauwick , A Kaba , J Delwaide , M Meurisse , P Honoré. University of Liege, CHU Liege, Belgium.
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IS ULTRA-SHORT COLD ISCHEMIA THE KEY TO ISCHEMIC CHOLANGIOPATHY AVOIDANCE IN DCD-LT? O Detry, A Deroover, S Cheham, H Ledinh, C Coimbra, E Decker, L Kohnen, MF Hans, J Joris, S Lauwick, A Kaba, J Delwaide, M Meurisse, P Honoré University of Liege, CHU Liege, Belgium Donation after circulatorydeath (DCD) livertransplantation (LT) hasbeenintroducedtopartiallyovercometheorgandonorshortage DCD LT haslower graft survival due toincreaseratesofprimary non-functionand graft loss due toischemiccholangiopathywithdifficulttotreat non-anastomoticbiliarystrictures Aim: Report theauthors‘ experience in DCD-LT, with a shortcoldischemia time andwithoutupperlimitagecriteria • Retrospective 10 yearsmonocentricexperience • Center-orientedallocationwithinthe Eurotransplant organisation • Noupperlimit DCD donoragecriteria • 70 consecutive DCD-LT • DCD in OR, withheparinanddonorcomforttherapy • Death on circulatorycriteria • 5 min no-touchperiod
DCD maybe a valuablesourceoflivergrafts • DWIT < 30 min & CIT < 5 hoursmayleadto a low rate of graft loss due to PNF and/orischemiccholangiopathy • With DWIT < 30 min & CIT < 5 hours, DCD donors > 60 yearssouldbeconsideredtoreallyincreasethecadavericdonorpool