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Understanding Hepatitis B Virus Immunology and T-Cell Receptor Variations

Explore the mechanisms of antibodies models, recombination of Ig genes, and TCR variations in the context of hepatitis B virus immunology. Discover insights into gene rearrangements, structural similarities between Ig and TCR, and more!

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Understanding Hepatitis B Virus Immunology and T-Cell Receptor Variations

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  1. Hepatitis B Virus

  2. Immunology: Antibodies

  3. Models for recombination of Ig genes V and J. A. Deletional joining occurs when the gene segments have the same transcriptional orientation (blue arrows). B. Inversional joining occurs when the gene segments have opposite transcriptional orientations.

  4. Class switching

  5. The T-Cell Receptor Variations on a Theme by Molecules of the Ig Superfamily!

  6. Structural similarities between Ig and TCR.

  7. Overview of TCR Recombination

  8. Production and Identification of cDNAs coding the TCR by subtractive hybridization.

  9. Germ-line organization of murine TCR genes.

  10. Gene Rearrangements

  11. Affinity constants and Roles of Co-receptors in TCR binding.

  12. TCR-MHC-peptide structures.

  13. TCR-MHC-peptide structures --top view with TCR α (red) and β (yellow) variable regions.

  14. HIV buds out of cells.

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