1. Cloning & Gene Therapy Notes • Warm up: You have 12 min to complete Woolly Mammoth Cloning. • HW check from yesterday.

2. DMD N Genetic Screening • Test DNA to detect genetic diseases • determines risk of havingor passing on a geneticdisorder • can detect genesrelated to an increasedrisk of cancer • can detect some genesknown to cause geneticdisorders

3. Gene Therapy • Is the replacement of faulty genes • Gene therapy replaces defective or missing genes, or adds new genes, to treat a disease.

4. Gene Therapy • Has many technical difficulties • Inserting gene into correct cell • Determining effect on other genes • Only way to cure genetic disease is to change the affected DNA

5. Cloning • A clone is a genetically identical copy of a gene or of an organism.

6. Cloning • Cloning occurs in nature. • bacteria (binary fission) • some simple animals (budding, regeneration) • Identical twins

7. Cloning • Mammals can be cloned through a process called nuclear transfer. • nucleus is removed from an egg cell • nucleus of a cell from the animal to be cloned is implanted in the egg

8. Benefits of Cloning • Human organ transplants • Save endangered species

9. Concerns of Cloning • Low success rate • Clones less healthy than original • Ethical controversy

10. Jurassic park