Bladder Cancer Trends in New Zealand )

1. No. 120 Bladder Cancer Trends in New Zealand) Anudini Ranasinghe, Diana Sarfati, Matthew Soeberg, Rodney Studd, Tony Blakely Wellington Hospital Department of Urology, Otago University Department of Public Health Posters Proudly Supported by: Introduction Bladder cancer ranks 9th in worldwide cancer incidence and has the highest rate of recurrence. Trends are difficult to interpret, however overall bladder cancer incidence trends have decreased in most western countries. Survival trends are variable worldwide. Results Incidence rates of bladder cancer in males were four times that of females across all groups. European/Others had higher incidence rates of bladder cancer compared with Māori, Pacific and Asian groups. The low income group had 10-20% higher rates of bladder cancer compared with the high income group. Trends in incidence rates increased in Europeans, Maori and all income groups. Overall a 21% (6-34%) decrease in excess mortality is seen for every 10 years of bladder cancer diagnosis. Annual percentage change in bladder cancer excess mortality from 1991-2004 was -2.3%. Survival improved in both Maori and non-Maori with no ethnic disparity (EMRR 1.02) (95%CI 0.63, 1.64). Gender disparity in survival was seen, with female EMRR 46% higher than males (95%CI 27-68%). • Aim • To describe the trend in bladder cancer incidence in New Zealand over a twenty year period between 1981 and 2004 by: • Gender • Ethnic group • Socioeconomic status • Bladder cancer relative survival rates were studied between the period of 1991 and 2004. Male incidence rates were four times that of females, European rates were higher than other ethnic groups and Incidence rates increased in all groups. Incidence rates were 10-20% higher in the Low income group. Methods Cancer Trends project data was used in this study which linked New Zealand cancer registry records to the five yearly New Zealand Census using probabilistic record linkage software (Quality-Stage) to create 5 separate Cohort studies. Incidence rates of bladder cancer (excluding CIS) from 1981-2004 were determined by gender, ethnicity and income group. Relative survival (RSR) and excess mortality (EMRR) analyses were conducted using sex-specific, sex- and ethnic-specific, and sex- and income-specific life-tables for 1991-2004. Both 1- and 5-year relative survival improved with no significant ethnic difference. Conclusions Bladder cancer incidence rates increased in New Zealand from 1981 to 2004. Males had up to 4 times the incidence rates of females; and Europeans had up to twice the incidence rates compared to other ethnic groups. There have been modest improvements in survival over this period; however, significant gender differences were seen in survival. 1-year relative survival improved for all income groups, however, 5-year relative survival only consistently improved for High income patients. Acknowledgements The Cancer Trends study was funded by the Health Research Council of New Zealand (06/256). References Blakely T, Shaw C, Atkinson J, Tobias M, Bastiampillai N, Sloane K, Sarfati D, Cunningham R. Cancer Trends: Trends in Incidence by Ethnic and Socioeconomic Group, New Zealand 1981–2004. Wellington: University of Otago and Ministry of Health, 2010.