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Testing for Heterogeneity (Sex differences)
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Testing for Heterogeneity (Sex differences) Danielle Dick, HermineMaes, Tim York
Sex Effects • Does the magnitude of genetic/environmental effects differ in males and females?
Sex Effects Females Males
Sex Effects Females Males aF = aM ? cF = cM ? eF = eM ?
Sex Effects • Does the magnitude of genetic/environmental effects differ in males and females? (QUANTITATIVE) • With OS pairs: Are the same genes/environments acting in males and females (QUALITATIVE)
Sex Specific Effects • Inspecting the correlations from DZ like-sex and opposite-sex pairs can alert you to the presence of sex-specific effects if the OSDZ correlation is markedly less than the SSDZ correlations.
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