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Raw Reads

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Raw Reads

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Presentation Transcript

  1. Integrative Analysis NGS Data Processing Variant Discovery and Genotyping …. Sample 1 reads Sample 1 reads Raw Reads Raw Indels Raw SVs Raw SNPs Input Mapping External Data SNPs Pedigrees Known variation Local Realignment Population structure Known genotypes Indels Duplicate marking Variant quality recalibration Structural Variation (SV) Genotype refinement Base quality recalibration Analysis ready reads Raw Variants Analysis-ready variants Output