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11 th Consortium Meeting, Barcelona, 27.6.2007

WP 6.3 Genomics and chronic inflammation. INFOBIOMED Pilot application WP 6.3. Genomics and chronic inflammation. Barcelona, 27.6.2007. Marja Laine DDS, PhD Academic Centre for Dentistry Amsterdam. 11 th Consortium Meeting, Barcelona, 27.6.2007. Demographic data. Environmental data.

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11 th Consortium Meeting, Barcelona, 27.6.2007

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  1. WP 6.3 Genomics and chronic inflammation INFOBIOMED Pilot application WP 6.3 Genomics and chronic inflammation Barcelona, 27.6.2007 Marja Laine DDS, PhD Academic Centre for Dentistry Amsterdam 11th Consortium Meeting, Barcelona, 27.6.2007

  2. Demographic data Environmental data Genomic data Phenomic data Microbiology data Life habits data Assessment / Annotation Programs External Database Periodontitis Data Warehouse (PDW) WP 6.3 Genomics and chronic inflammation 11th Consortium Meeting, Barcelona, 27.6.2007

  3. WP 6.3 Genomics and chronic inflammation Periodontitis Data Warehouse (PDW) • About 800 periodontitis patients/controls • Privacy protected • Remote accessibility via dedicated server at VUMC • Integration of a new database of 750 new patients • Inclusion of biochemical markers and physiological parameters • Instruction manual for the PDW in Dutch and English 11th Consortium Meeting, Barcelona, 27.6.2007

  4. WP 6.3 Genomics and chronic inflammation Periodontitis Data Warehouse: • The PDW has been constructed and is functional. • The PDW infrastructure and concepts can be applied to other diseases. • Barrett’s oesophagus (Erasmus University, Rotterdam) Data mining – Vassilis Moustakis, FORTH 11th Consortium Meeting, Barcelona, 27.6.2007

  5. WP 6.3 Genomics and chronic inflammation Participants: ISCIII, Spain Fernando Martín UPM, Spain Victor Maojo Guillermo de la Calle Velasco David de Perez University of Leicester, UK Anthony Brookes University of AVEIRO, Portugal Antonio Sousa Pereira José Luis Oliveira Luis Coelho Custodix, Belgie George de Moor Brecht Claerhout FORTH Institute for Computer Sciences, Greece Vassilis Moustakis Academic Center for Dentistry Amsterdam Dept. of Periodontology Bruno G. Loos, activity leader Ubele van der Velden Section of Microbiology Marja L. Laine Arie Jan van Winkelhoff Vrije Universiteit Medical Center Lab. of Immunogenetics Salvador Pena Bart Crusius Servaas Morre Dept. of Informatics Carol van der Palen Francis Lessmann 11th Consortium Meeting, Barcelona, 27.6.2007

  6. WP 6.3 Genomics and chronic inflammation Periodontitis Data Warehouse - summary • about 800 patients/controls • genetic, microbiology, severity, intermediate phenotype • together with Custodix finalizing the privacy protection • external named user access (VPN-key) • external accessibility (dedicated server) • finalizing stage: data mining, visualization with Forth

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