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Analysis of Ion Channel Modulators on Cellular Responses

This study investigates the effects of various ion channel modulators, including L-NA, Mibefradil, and NNC 55-0396, on cellular responses in controlled experiments. Figures illustrate the impact of TRAM-34, Apamin, Charybdotoxin, and Ouabain on cellular behaviors. Each illustrated figure presents control comparisons, enhancing our understanding of how these compounds influence ion channel activity. Results indicate differential responses based on compound application, providing insights into potential therapeutic avenues in cellular signaling modulation and ion channel research.

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Analysis of Ion Channel Modulators on Cellular Responses

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  1. Figure 1 B Control L-NA + indo + ibTx A C D

  2. Figure 2 A Mibefradil • ∕ ∕ ∕ ∕ ∕ ∕ ∕ ∕ B NNC 55-0396 • ∕ ∕ ∕ ∕ ∕ ∕ ∕ ∕ C NNC 55-0396 Nifedipine •

  3. Figure 3 Control TRAM-34 A B Apamin TRAM-34 + Apamin C D E

  4. Figure 4 Control Charybdotoxin A B Charybdotoxin + Apamin C D E

  5. Figure 5 4-AP A Control B Ouabain • C

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