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Mouse BIRN

Mouse BIRN. Data Integration Across Scale. Diverse Participants and Data Types. Informatics Center for Mouse Neurogenetics. UCLA LONI. (UTHSC). (Drexel). UCSD (NCMIR). Caltech (Beckman). Duke (CIVM). Goals.

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Mouse BIRN

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  1. Mouse BIRN Data Integration Across Scale

  2. Diverse Participants and Data Types Informatics Center for Mouse Neurogenetics UCLA LONI (UTHSC) (Drexel) UCSD (NCMIR) Caltech (Beckman) Duke (CIVM)

  3. Goals Flexible and Extensible tools to share and mine multi-scale structural and functional mouse brain data • Digital Atlases • Automated Image Processing • Integrate Gene Expression Efforts • Integrated Interface Applications Focus on: Neurodegenerative Diseases

  4. Atlases as Intuitive Integrative Environment Spatially Coregistered Images in Database Ontologies Mouse BIRN Atlasing Toolkit (MBAT) Coregistered Atlas Modules Web Based Resources WebQTL BAMS

  5. Data Integration Framework Data Upload Organize Describe Database Management Data Grid Remote Databases Local Databases Data Processing Data Acquisition Integrate Share Discover Analyze Visualize

  6. Data Integration Integrate Databases Clinical/ Behavioral Spatial Information Standards Discover Imaging Semantic Information Database Integration Microarray EXTERNAL DATA OTHER INFORMATION

  7. Visualize, Analyze and Compare

  8. Mouse BIRN Data Freely available, powerful extensible Tools MBAT and integration tools Facilitate sharing other types of data Tied into and drive the BIRN infrastructure To Investigate: The disease mechanism Potential therapies Link to human Share

  9. Additional Information BIRN: http://www.nbirn.net/research/mouse/index.shtm MBAT: http://www.nbirn.net/tools/mbat/index.shtm Mouse BIRN Wiki: http://www.nbirn.net/research/mouse/index.shtm PI: Arthur Toga toga@loni.ucla.edu Project Manager: Jyl Boline - jboline@loni.ucla.edu Mouse BIRN Information

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