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Learn about the stages of the cell cycle - interphase, mitosis (PMAT), and how PMAT controls cell division. Discover the roles of prophase, metaphase, anaphase, and telophase in preparing, dividing, and finishing the process. Understand the significance of cyclins and CDK in regulating the cell cycle and the consequences of uncontrolled cell growth leading to tumor formation and cancer.
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Cell Cycle Interphase Mitosis
Interphase • Cell normally functioning • Phase cell is in most of the time • G1, G0, S, G2
Mitosis-PMAT • Prophase-Prepare • Metaphase-Middle • Anaphase-Apart • Telophase-THE END
Prophase-PREPARE • Cell PREPARES to divide • Centrioles get into place • Spindle fibers form • Chromosomes condense • Nuclear envelope dissolves
Metaphase-MIDDLE • Chromosomes line up in the MIDDLE of the cell
Anaphase-APART • Chromosomes are pulled APART by the centrioles and spindle fibers
Telophase-THE END • The chromosomes are at each end of the cell and nuclear envelops form • The cell divides in two-Cytokinesis • THE END
What does PMAT stand for? Prophase Metaphase Anaphase Telophase Prepare Middle Apart THE END
Controls on Cell Division • Cells only divide when growth is needed • Cyclins and Cyclin Dependent Kinases (CDK) are proteins that regulate the timing of the cell cycle
Uncontrolled Cell Growth • When cells lose the ability to control growth it results in a mass of cells called a tumor. • Benign tumors • Do not metastasize (spread) • Malignant tumors-Cancer • Metastasize