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the function of the nucleus within the cell

the function of the nucleus within the cell. 20 January 2012. Question:. A healthy cell in the duodenum responsible for producing amylase is found to have an abnormally low concentration of the enzyme. What could be the cause of this anomaly ? What do we need to know to answer this question?.

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the function of the nucleus within the cell

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  1. the function of the nucleus within the cell 20 January 2012

  2. Question: • A healthy cell in the duodenum responsible for producing amylase is found to have an abnormally low concentration of the enzyme. What could be the cause of this anomaly? • What do we need to know to answer this question?

  3. 4 2 3 1 5 7 8 6

  4. cell membrane smooth ER nucleus ribosome mitochondrion rough ER Golgi body lysosome

  5. transcription and translation • http://www.youtube.com/watch?v=41_Ne5mS2ls

  6. protein synthesis • The nucleus receives a chemical signal to make a specific protein. • The DNA message for the protein is copied into RNA. • RNA leaves the nucleus through a nuclear pore. • The RNA message is delivered to a ribosome • The ribosome makes the protein. • The manufactured protein enters the endoplasmic reticulum (ER). • A vesicle forms at the end of the ER, and carries the protein to the Golgi. • The Golgi body repackages the protein for transport out of the cell. • A vesicle forms off the end of the Golgi body to carry the protein to the cell membrane.

  7. Back to the original question… • A healthy cell in the duodenum responsible for producing amylase is found to have an abnormally low concentration of the enzyme. What could be the cause of this anomaly? • error in nucleotide sequence • error in transcription from DNA  mRNA • error in translation from mRNA  protein • other possibilities?

  8. interesting/useful links • DNA structure: http://www.youtube.com/watch?v=qy8dk5iS1f0 • foldit: http://fold.it/portal/ • Protein synthesis: http://www.wisc-online.com/Objects/ViewObject.aspx?ID=AP1302

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