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INTAS’ policy instruments for integration of NIS Food Science into the ERA Paul Beckers, Scientific Officer for Life Sciences. The essence of INTAS Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions. Outline. The essence of INTAS

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  1. INTAS’ policy instruments for integration of NIS Food Science into the ERA Paul Beckers, Scientific Officer for Life Sciences

  2. The essence of INTAS Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions Outline

  3. The essence of INTAS Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions Outline

  4. INTAS • INTAS – International Association for the promotion of co-operation with scientists from the New Independent States of the former Soviet Union (NIS) Established in 1993 to: • preserve the best NIS scientific capabilities • foster social & economic progress • support international scientific collaboration for mutual benefit

  5. Members & Partners 25 European Union member states + European Community Bulgaria Iceland Israel Norway Romania Switzerland Turkey 12 Partner Countries Armenia Azerbaijan Belarus Georgia Kazakhstan Kyrgyzstan Moldova Russia Tajikistan Turkmenistan Ukraine Uzbekistan 33 Members

  6. INTAS budget Major part comes from the European Community (International Cooperation INCO) 2002 - 2006 ~70 M Euro In kind contributions from members + financial participation from members & NIS in jointly funded projects 2002 – 2006 ~10 M Euro

  7. INTAS Priorities • Search for scientific excellence • Cover allscientific areas • Include fundamental andapplied research • Support internationalscientific collaboration • Select proposals on the basis of independent evaluations • Allocate min. 75% of the funds to NIS teams • Focus on young scientist initiatives • Encourage NIS partners to participate in FP6 does notfund military research & abstains from any political and commercial activities. All participants in INTAS funded projects must comply withALL applicable national laws. If in doubt (e.g. field trips), check with the relevant authorities

  8. ”Cooperation activities with Russia and other NIS countries will be carried out in particular through the INTAS structure set up jointly by the Community and the Member States.” (Council Decision adopting the specific FP6 programme “Integrating and strengthening the European Research Area”) INTAS and FP62003-2006

  9. Agreements INTAS Agreements on Scientific Cooperation for: • "framework" agreements • tax exemptions of INTAS grants • duty-free import of INTAS-funded scientific equipment • official contact person in ministry / state committee

  10. INTAS Contacts in NIS ININ Help provided to scientific communities in the NIS About INTAS through the INTAS Information Desks (Armenia, Belarus, Georgia, Russia)  complete list and contact details on www.intas.be in “Links” About FP6 and European Programmes through the INTAS National Information Points (Armenia, Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Ukraine, Uzbekistan), National Contact Points (Russia)  complete list and contact details on www.intas.be in “ININ”

  11. INTAS Activities • Calls for proposalsfor research and network projects: open calls, thematic & jointly funded calls • Pre-/Post PhD Fellowshipsfor Young NIS scientists • Accompanying Measures : Summer Schools, Infrastructure Actions, Strategic Scientific Workshops • Innovation Grants • ININ(INTAS FP6 NIS Information Network): Promotion of NIS participation in FP6 & ERA A newly developed IT platform = submission + evaluation + management ON-LINE

  12. The essence of INTAS Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions Outline

  13. To be used for Open Call, Thematic and/ or Co-funded Calls, Regional activities Young Scientist Fellowships, Innovation Grants, Accompanying Measures, ININ activities INTAS 2005-2006  Budget 2005-2006 under FP6 ~ 33,5 M Euro

  14. The essence of INTAS Pre-view of INTAS activities 2005-2006 FP6 Information activities (ININ) Highlights of Food Call 2000 Conclusions Outline

  15.  INTAS FP6 NIS Information Network ININ Established to promote the involvement of NIS scientific communities in European Research Area (ERA), and their participation in Sixth Framework Programme for Research & Technology(FP6)

  16.  ININ Concept ININ Activities • Information dissemination & networking • Scientific community-targeted activities / events • Support to NIS FP6 NIS National Information Points (NIPs)

  17.  ININ Information dissemination ININ • POISK FP6 series (11 articles ’03, 12 articles ’04) • Regular mailings • INTAS Website

  18.  National Information Points (NIPs) ININ Typical tasks: modelled on the NCPs • Information & awareness raising about ERA, FP6 & international S&T co-operation • Advice, assistance & training • “Signposting” (feed-back & reporting) • Monitoring of domestic research communities

  19.  National Information Points (NIPs) ININ Status • NIP structures appointed in 10 NIS • NIP coordinators information & training workshops (meetings with FP6 officials & NCPs, spring ‘03) • NIP concept papers (long term objectives & strategy) • Agreements for ININ support to NIPs (Sept. 2003 ......2005) • NIP capacity-building training courses (March-April ’04)

  20.  ININ next steps ININ • More scientific community-targeted activities: • Brokerage events scheme • Reflection on other partner search support activities • Increased cooperation with INTAS members & international organisations

  21. The essence of INTAS Review of INTAS 1992-2003 Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions Outline

  22.  Scope Food Call 2000 • Production, processing and distribution of food. • Environmental impact of food production, processing and distribution. • Improvements in human and animal health as a result of plant and animal breeding, dietary changes, reduced toxicity, quality control, food safety, etc. • Social and economic consequences of changes in food production, processing and distribution.

  23.  Facts and Figures Food Call 2000 • Budget 1.2 M€ • 16 Funded projects • 80 Teams • 22 Countries (NIS: 3UZ; 11UA; 25RU;1BY; 2AM; 3GE; 3KZ; 2MD.INTAS: 2NL; 4IT; 1IL; 1IE; 2GR; 1FR; 1FI; 2ES; 1DK; 4DE; 1CH; 6UK; 2SE; 3AT)

  24. Food Call 2000

  25. The essence of INTAS Review of INTAS 1992-2003 Pre-view of INTAS activities 2005-2006 FP6 Information activities Highlights of Food Call 2000 Conclusions Outline

  26. INTAS offers more than 10 years of routine in funding EU-NIS collaborative science INTAS keeps developing funding instruments/ structures (ININ) for integrating NIS scientists into FP/ERA A large community of food scientists from NIS and INTAS member states participates in INTAS projects INTAS is looking for partnerships in collaborative and co-funded actions Conclusions

  27. For Life Sciences: Paul.Beckers@intas.be In general: INTAS@intas.be Contact

  28. Highlights Food Call 2000 003-0471 Bases for a rational control of foodborne listeriosis: a paneuropean initiative Teams: University of Leon, Spain Veterinary School, University of Bristol, UK All Russia Meat Institute, Moscow, Russia Gamalleya Research Institute of Epidemiology and Microbiology, Moscow, Russia Research Institute of Veterinary Virology and Microbiology, Pokrov, Russia Institute for Milk Hygiene, Milk Technology and Food Science, Vienna, Austria Duration: 01-10-2001 till 30-09-2005

  29. Highlights Food Call 2000 • Bases for a rational control of foodborne listeriosis: a paneuropean initiative • Objectives: • Elaboration of rapid methods for the detection and typing of Listeria monocytogenes strains present in the food chain, from the farm to the ready-to-eat food. • Investigation of Listeria monocytogenessurvival, growth and virulence in environmental models, simulating natural habitants like soil, food and animal tissues; • Comparative epidemiological analysis of clinical and food-borne isolates of L. monocytogenes from all around Europe to get insight into the relationships between epidemiological, physiological and virulent characteristics of the strains; • Study of the genetic and physiological bases of listerial survival, growth and virulence expression under specific stress conditions observed in food models.

  30. Highlights Food Call 2000 • Bases for a rational control of foodborne listeriosis: a paneuropean initiative • Outcome (so far): • RFLP analysis supports hypothesis of three phylogenetic lineages of L. monocytogenes • New method to differentiateL. monocytogenes from non-pathogenic Listeria spp. based on lecithinase activity on charcoal-supplemented agar media • Establishment of the State Standard of the Russian Federation for methods of detection of Listeria monocytogenes in food products • 1 Patent (Russian Federation N2196827; adopted 20-01-2003) • 3 joint papers in international journals; 5 in national journals; 1 thesis

  31. Highlights Food Call 2000 Bases for a rational control of foodborne listeriosis: a paneuropean initiative Outcome (so far): Figs. Rapid method of identification of L. monocytogenes food isolates based on the induction of lecithinase in charcoal-supplemented egg yolk medium. (From: Ermolaeva et al. 2003, Int. J. Food Microbiol. 82:87-94; Ermolaeva et al. 2004. Mol. Microbiol. 52:601-611.)

  32. Highlights Food Call 2000 003-0727 Prevention of food spoilage by suppression of phenoloxidase, peroxidase and growth of pathogenic microflora by use of natural inhibitors of plant origin Teams: University of Murcia, Spain John Innes Centre, Norwich, UK Kazan Institute of Biochemistry and Biophysics, Kazan, Russia Institute of Bacteriophage, Microbiology and Virology, Tblisi, Georgia Georgian State Subtropical Institute, Kutaisi, Georgia Durmishidze Institute of Biochemistry and Biotechnology, Tblisi, Georgia Duration: 01-07-2001 till 31-05-2004

  33. Highlights Food Call 2000 • Prevention of food spoilage by suppression of phenoloxidase, peroxidase and growth of pathogenic microflora by use of natural inhibitors of plant origin • Objectives: • to obtain and characterize highly active inhibitors of phenoloxidases and peroxidases isolated from different plants • to determine the mechanism of inhibition of plant phenoloxidases and peroxidases by natural inhibitors of plant origin • to determine the antibacterial activity of isolated biologically active substances towards different groups of food spoilage microorganisms and pathogenic bacteria • to determine the effect of compounds of plant origin on the energy exchange of plants • to investigate the effect of plant inhibitory preparations on the generation of superoxide radicals and the activity of ascorbate oxidase in model plant cells • to prevent spoilage, extend shelf life and preserve the nutritional value of food products using natural inhibitors of plant origin.

  34. Highlights Food Call 2000 • Outcome (so far): • Several phenoloxidases and peroxidases from different plant sources have been isolated and characterized. • Purification protocols for natural inhibitors from tea (Cameliia sinenisis L) leaves and pomegranate (Punica granatum) peel have been developed. • New, improved types of the beer and butter with longer shelf lives and increased nutritional value have been produced by adding these natural inhibitors and green / black tea extracts to the currently marketed products. • The data demonstrated that natural plant inhibitors can be used for the prevention of bacterial spoilage and contamination of food products while maintaining a viable, high level of beneficial microflora. • First evidence that the prophylactic effect of green tea drinking on certain forms of cancer, suggested by epidemiological studies, is due to the inhibition of dihydrofolate reductase (DHFR) by (-)-epigallocatechin gallate EGCG. • 11 papers in international journals (5 jointly; 2 in press; 4 submitted); 3 in national journals; 1 publication in a book; 4 abstracts in proceedings; 1 patent

  35. Highlights Food Call 2000 003-0876 New biotechnologies for production of food grade lactic acid from raw starchy material Teams: Technical University of Hamburg- Harburg, Germany Wageningen Agricultural University, The Netherlands Republican Centre for Deposition of Microorganisms, National Academy of Science, Armenia St. Petersburg State Technological Institute (technical University), Russia Institute of Microbiology, National Academy of Science, Minsk, Belarus Duration: 01-08-2001 till 31-07-2003

  36. Highlights Food Call 2000 New biotechnologies for production of food grade lactic acid from raw starchy material Objectives: To develop and evaluate the biotechnological potential of the use of amylolytic lactobacteria, particularly Streptococcus bovis, possessing amylolytic activity, for food grade lactic acid production from raw starch and starchy materials

  37. Highlights Food Call 2000 • New biotechnologies for production of food grade lactic acid from raw starchy materialOutcome (so far): • A culture collection of efficient amylolytic lactobacteria with databases has been established. • The different methods for maintenance and long-term conservation of four strains of S. bovis have shown the efficiency of application of liquid nitrogen and freeze-dried lyophilization with certain polysaccharides. • Economic indices of production of food grade lactic acid by the use of S. bovis exceed those of actually existing microbiological production • Technique for production of lactate based polymeric films was developed • Very important advantage for large-scale implementation of S. bovis is the possibility to use raw starch as a starting material, particularly starchy wastes in many productions. • 3 papers in international journals (2 jointly published); 8 in national journals (3 jointly); 14 abstracts in proceedings; 2 patents

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