clementine-ball
Uploaded by
42 SLIDES
751 VUES
420LIKES

End-replication problem

DESCRIPTION

End-replication problem. Repetición telomérica : TTAGGG. Mecanismo de acción de la telomerasa. Extremo 3´ DNA telomérico. Actividad de telomerasa: Ensayo TRAP. Actividad de telomerasa: Ensayo TRAP. Límite de Hayflick. Determinación del largo del telómero.

1 / 42

Télécharger la présentation

End-replication problem

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. End-replication problem

  2. Repetición telomérica: TTAGGG

  3. Mecanismo de acción de la telomerasa

  4. Extremo 3´ DNA telomérico

  5. Actividad de telomerasa: Ensayo TRAP

  6. Actividad de telomerasa: Ensayo TRAP

  7. Límite de Hayflick

  8. Determinación del largo del telómero

  9. Reducción telómerica en sucesivas generaciones

  10. Estabilización del telómero por la telomerasa

  11. Cancer and telomerase What price immortality?

  12. Blasco (2005) Nature Reviews Genetics6, 611-622

  13. Extensión de la vida de células somáticas por expresión de telomerasa

  14. ¿Qué pasa con estos ratones? • mRT -/- • p16INK4a -/- ; ARF -/- • mRT -/- ; p16INK4a -/- ; ARF -/- • p53 -/- • p53 -/- ; mRT -/-

More Related