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End-replication problem

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End-replication problem. Repetición telomérica : TTGGGG. Mecanismo de acción de la telomerasa. Estructura del telómero: T-loop. LeBel and Wellinger (2005) J. Cell. Sci. 118 , 2785-2788. Límite de Hayflick. Estabilización del telómero por la telomerasa. Cancer and telomerase.

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End-replication problem

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  1. End-replication problem

  2. Repetición telomérica: TTGGGG

  3. Mecanismo de acción de la telomerasa

  4. Estructura del telómero: T-loop

  5. LeBel and Wellinger (2005) J. Cell. Sci. 118, 2785-2788

  6. Límite de Hayflick

  7. Estabilización del telómero por la telomerasa

  8. Cancer and telomerase What price immortality?

  9. Blasco (2005) Nature Reviews Genetics6, 611-622

  10. Extensión de la vida de células somáticas por expresión de telomerasa

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