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SSRL User’s Organization Executive Committee Activities 10/05-9/06

SSRL User’s Organization Executive Committee Activities 10/05-9/06. Joy Cooke Andrews SSRLUO-EC Chair September 2006 . Coordination with users Diverse Group Academic, industrial, research, students Many fields: e.g. Materials, Biological, Environmental

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SSRL User’s Organization Executive Committee Activities 10/05-9/06

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  1. SSRL User’s OrganizationExecutive CommitteeActivities 10/05-9/06 Joy Cooke Andrews SSRLUO-EC Chair September 2006

  2. Coordination with users Diverse Group Academic, industrial, research, students Many fields: e.g. Materials, Biological, Environmental With User Research: Optimize experimental setup, facilities, safety training E.g. fill schedule, SSRL-specific safety training Optimize proposal selection with Peer Review Panel Interact with Director on goals, vision Brighter light, new beam lines, facilities, etc. User’s Meetings Presentations, Student posters, Awards Advocacy Developing database: information on research fields, home institution, e-mail, zip codes etc. Main Function of SSRL EC

  3. User Facilities Illuminate Ancient Secrets Last year two experiments detailing how synchrotrons helped to reveal ancient secrets received significant media coverage: Beethoven’s lead poisoning and deciphering Archimedes’ text. Funded by an anonymous collector, scientists from the Walters Art Museum, Stanford University and SSRL used x-ray fluorescence to decipher the Archimedes Palimpsest, covered over by a 20th Century forgery, the only source for at least two previously unknown treatises by the Greek scholar. A photograph of one page of the Archimedes Palimpsest. Visible and UV light cannot see Archimedes' text under the gold painting done by a 20th Century forger. X-ray fluorescence imaging reveals the hidden text. (Images provided by Will Noel, The Walters Art Museum, Baltimore) Intensity of Pb x-ray fluorescence from a standard hair (SN-1) with 6 ppm of lead compared to that of a hair from Beethoven (LVB) as determined at APS. A distant relative of Beethoven sent bone fragments to the Pfeiffer Treatment Center who worked with APS scientists to confirm massive amounts of lead as the cause of the composer’s chronic illness. Page 6

  4. New Organic Conductor for Electronic Devices Scientists have developed a new organic polymer that can be laid down using simple printing techniques rather than the expensive and elaborate methods used to process silicon, 6 times faster than previous organic polymers. Now just as fast as silicon plus much cheaper, this inexpensive organic conductor could be used in areas where silicon struggles to compete, eventually slashing the cost of transistors, PDA’s, flat panel screens and bringing electronic paper into common use. Research team includes Merck Chemicals (UK), Palo Alto Research Center (California), Stanford University, and SSRL Crystal Power. New semiconducting plastics form large crystals that help whisk electrical charges at higher speeds than ever before. McCulloch et al., Nature Materials, March 2006. Science (311), March 2006. Page 9

  5. Structural Insights into Human Innate Immunity Scientists are analyzing sensors in human cells that detect viruses, bacteria, fungi and parasites. This will be important for pharmaceutical companies when designing viral and bacterial immunizations that can quickly counter specific threats due to bioterrorism and/or diseases such as avian flu. Overall structure of human TLR-3. Funded by the National Institutes of Health Choe et. al., Science309 581-5 (2005) Structure showing the locations of the positive patches and leucine-rich repeats (LRR) implicated in binding. Page 12

  6. Next User’s Meeting October 12-13 2006 Special Session October 13 Open Forum with Jo Stohr Advocacy Session Oktoberfest Beer

  7. Melvin P. Klein Scientific Development Award Honors MP Klein (1921-2000) Up to $1000 for student to disseminate scientific results based on work at SSRL Fund currently growing, through SSRL Dale E. Sayers Fellowship Through North Carolina State U For mentoring of students 2 New Funds

  8. Advocacy: Formation of SNUG SNUG Delegation to DC April 06

  9. Global physical science message vs lobbying for a specific group or even just for DOE facilities Users of the facilities are in the best position to appeal to Congress Particularly at our local representatives’ offices Present the potential applications of the basic research done at the facilities We can help our DOE advocates in Washington by Responding to their letters of support Providing them with materials to help present the case for physical science Helping to educate industrial representatives so that they too can present the case for physical science research and its applications Specific long term tasks Broaden the user database Survey intended for each facility to identify local user’s organizations, their leaders and activities Become aware of the budgetary seasons, e.g. when the budget is with OMB, on the Hill Time our meetings to best target these time periods. Yearly, develop a written notebook that identifies current research from the facilities and its potential applications (particularly to goals that interest the administration such as national defense, etc.) SNUG goals

  10. Eventually develop teams from each light source to visit Washington DC, e.g. One in December to visit with appropriations and authorizing committees All in February/March. The Feb/Mar meeting should cover all local reps from users that we recruit A third as needed. Messages, again, should be global physical science. Additional appearances for the above teams: Press conferences, briefings for industrial lobbyists (December), congressional hearings (spring) Workshops at annual user’s meetings to train users in advocacy, especially visiting local representatives and having reps visit local research facilities. Letter writing to local papers, speaking at local (eg Kiwanis) clubs to explain what we do and why it is important. Develop a user central to support this, e.g. the American Physical Society. Further long-term priorities

  11. SNUG meetings 08/05, 10/05: Unified physical science message Letter to Bodman 09/05 from SNUG EC chairs Synchrotron, neutron facilities are a cornerstone of national science infrastructure Acknowledges DOE support of these facilities, and Bodman’s remarks in support of science Encourages strong F’07 budget for physical science Offer to help – to meet with Bodman to convey our enthusiasm, and to determine how we can best help Letter writing campaign from SNUG facilities to Joshua Bolton, OMB SSRL and sister synchrotron and neutron facilities are among “the true success stories of the Office of Science” (per Orbach letter) Operational stresses threaten to compromise mission, esp. as related to six key areas: homeland security, national defense, energy security, economic growth, biomedicine, training of future science and engineering workforce Request meeting budgetary request for Office of Science that will allow facilities to thrive User’s Survey User Letter writing (to follow up on budget increases of 14%) To representatives, thank you for support, encouraging continued support Visit to Washington DC April 2006, (October 2006?) SNUG and its activities

  12. April 9-11 2006 Reps from 4 light sources, 3 neutron sources Briefing document: Budget information and implications Physical science highlights (esp with applications in homeland security, national defense, energy security, economic growth, biomedicine, training of science and engineering workforce) Target: industrial collaborations Budget is good, ensure physical science message gets out to ensure that we keep it Briefing document can be brought by users to local representatives’ offices Washington DC visit Spring 06

  13. Advanced Photon Source Intense Pulsed Neutron Source National Synchrotron Light Source (NSLS2 upgrade approved) Advanced Light Source Spallation Neutron Source (under construction) Stanford Synchrotron Radiation Laboratory Linac Coherent Light Source (under construction) High-Flux Isotope Reactor Los Alamos Neutron Science Center DOE Synchrotron and Neutron Facilities The Synchrotron and Neutron Users’ Group (SNUG) represents: • 4 High-Flux Neutron Sources • 5 Photon Light Sources • Including two under construction

  14. Who We Are The Synchrotron and Neutron Users’ Group (SNUG) represents over 9,000faculty,student,industrialandgovernmentscientists. Their research is critical to every sector of the economy: • Materials Chemistry and Nanotechnology • Electronic Materials and Devices • Energy Production, Storage and Conversion • National Security • New Medicines and Disease Treatments • Environmental Sciences • Human and Molecular Biology Approximately 600 scientists from over 160 companies representing technology, manufacturing, energy, chemical, and bio-pharmaceutical industries use the synchrotron and neutron facilities.

  15. Synchrotron Facilities: Produce ultra-high intensity light frominfra-redto visible lightto ultraviolet to X-rays. Enable us to see how nature and human-made devices work at the atomic and nanoscale, and directly observe biological and chemical processes. Neutron Facilities: Penetrate deep into materials to give precise information about positions and motions of atoms in the interior of a sample, allowing a more detailed understanding of structure and properties. WHY Are These Machines So Valuable? Only the federal government can design, build and operate facilities large and sophisticated enough to be of continuing use to thousands of individual industry and government researchers.

  16. Synchrotrons and neutron light sources were inventions of fundamental physics developed at U.S. laboratories. While the U.S. invented these machines, in recent years other nations of the world have hastened to build their own. Competition for Synchrotron and Neutron Sources Considering only beam ports on 3rd generation synchrotrons worldwide, by 2009 the U.S. will be outnumbered by the rest of the world 7:1

  17. Hydrogen Technology Clean Fuels Solar Cells Nuclear Waste Environmental Clean-Up Studies of Viruses, Bacteria and New Techniques in Immunology Alzheimer’s Disease Earthquake Prediction Advanced Computing Data Storage Examples of Work Critical to Industry

  18.  Steps Toward Hydrogen Vehicles Synchrotron research has shown that carbon nanotubes, 50,000 times more narrow than a human hair, are a promising material for storing hydrogen safely, efficiently and compactly. The DOE Freedom CAR program has set the goal of a material that can hold 6% of the total weight in hydrogen by the year 2010. Theoretical calculations indicate they may exceed these goals substantially. Funded by DOE, NSF and Global Climate and Energy Project (alliance of scientific researchers and leading companies in the private sector, including ExxonMobil, General Electric and Schlumberger) Nikitin et. al., Phys Rev Lett. 95, 225507 (2005) Scientists at NSLS are studying nanoparticles made of the compound ceria that couldimprove the ability of catalytic converters to lead to more efficient ways to generate hydrogen fuel because it is clean and renewable. Funded by DOE and NSF Liu, et al. J. Phys. Chem. B. 108, 2931 (2004)

  19. Crystal Structures of Real Materials The data from synchrotrons - 200-500,000 better than from laboratory sources – enables the precise delineation of complex crystal structures of which most materials are comprised. This new understanding improves the performance of many industrial materials, ranging from common expectorants in decongestants on the drugstore shelf to components in efficient refrigerators with no moving parts. Funded by BP/Innovene

  20. Understanding Viral Transmission:Bacterial Syringes Nature has devised biological syringes (right) that function exactly as they look to mainline toxins or virulent proteins into a host cell. The workings of these syringes is of enormous interest to public health, pharmaceutical designers and other scientists, who can now use this information to thwart these mechanisms. Researchers have uncovered the needle complex found in bacteria such as Salmonella and E.coli and used by the bacteria to deploy diseases ranging from food poisoning, bubonic plaque, and whooping cough. Funded by the Howard Hughes Medical Institute and the National Institutes of Health Ribbon and surface representation of the modeled 24-subunit ring which makes up the base of the needle

  21. Preventing Plaque Formationin Alzheimer’s Disease In Alzheimer’s Disease (AD), the brain contains a buildup of a misfolded protein, called “plaque,” that is believed to kill brain cells. It is thought that normal metal ions in the brain play a role in plaque formation. At the NSLS and APS, scientists showed that cooper and zinc ions accumulate in AD, implicating that metal ions play a role in plaque formation. These findings provide a better understanding on how AD plaques form and can be used for developing preventative drugs. Funded by the National Institutes of Health Eli Lilly is in the process of starting a collaboration to extend this work

  22. More Powerful Computing for the Information Age Improved computational power comes from shrinking transistors to squeeze more of them into a microprocessor. Extreme Ultraviolet (EUV) Lithography is the likely next generation technology to make those continued improvements possible. The pioneering work done with synchrotron radiation has driven this technology forward toward commercialization. Printed image showing 39 nm features EUV lithography exposure tool using synchrotron radiation Supported by consortium including: Sandia, LLNL, LBNL, Intel, Advanced Micro Devices, Micron Technology, Infineon Technologies, and IBM Current technology will allow manufacturers to print circuits as small as 0.1 micron in width (or 1/1,000th the width of a human hair). EUV lithography technology will extend this down to 30 nm or less (.03 microns), making processors 8 times more powerful than they are today.

  23. Congress in the past few years has worked within fiscal limits to restore science, math and education funding. It has taken several important initiatives this year. The President has joined the effort in a major way for FY 2007: “We must continue to lead the world in human talent and creativity.Our greatest advantage in the world has always been our educated, hardworking, ambitious people – and we're going to keep that edge. Tonight I announce anAmerican Competitiveness Initiative, to encourage innovation throughout our economy, and to give our nation's children a firm grounding in math and science.” “I propose to double the federal commitment to the most critical basic research programs in the physical sciences over the next 10 years.This funding will support the work of America's most creative minds as they explore promising areas such asnanotechnology, supercomputing, and alternative energy sources.” President George W. Bush State of the Union Address January 31, 2006 The Nation Needs to Keep Basic Research Moving Forward!

  24. The U.S. needs to optimize knowledge-based resources, particularly in science and technology Scientific progress and competitive position of U.S. depends on how wisely we invest in research capability User research has broad applications of national interest, including: energy efficiency and supply toxic waste cleanup bioterrorism and disease detection electronics, telecommunications and manufacturing After several decades of constrained spending, support for the American Competitiveness Initiative is essential in FY 2007 to reinvigorate the U.S. science base, including efficient maintenance and use of the large U.S. investment in synchrotron facilities and neutron facilities FY 2007 Funding Needed to “Right the Ship”

  25. SSRL EC members also participated in “Listen to Washington” event at SLAC Further coordination with SLAC, Fermilab, etc. Visit local congressmen, senators Common User database to find users in various districts Common literature: unified Office of Science Message followed by one-page summaries from labs Possible joint visits to Washington DC Other Ideas? Coordination with SLAC

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