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This article discusses the barriers and facilitators to implementing guideline-based care for sickle cell disease, with a focus on acute pain management. It also explores existing and upcoming guidelines and provides strategies for implementation at the institutional level.
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Implementing Guidelines for Sickle Cell Disease Management into Practice Marsha J. Treadwell, PhD 5 September 2019
Disclosure No one involved in the planning or presentation of this activity has any relevant financial relationships with a commercial interest to disclose
Objective • Describe barriers and facilitators to the implementation of guideline based care in sickle cell disease within healthcare institutions, with particular focus on acute pain management
Guidelines for SCD Care • Early guidelines largely consensus based • American Pain Society – Management of Acute and Chronic Pain in Sickle Cell Disease • NHLBI offered evidence based guidelines in 2014 • Essential to determine pain characteristics, associated symptoms, location and intensity of pain based on patient self-report Yawn et al JAMA 2014; 312: 1033- 48 Benjamin et al APS Clinical Practice Guidelines Series #1 1999
Existing and Upcoming Guidelines • National Institute for Health and Care Excellence (NICE) guidelines – UK • American Society of Hematology – to be released 2019 • American College of Emergency Physicians - Emergency Department Sickle Cell Care Coalition - 2019 • California state guidelines – under leadership of Dr. Vichinsky - 2019 • Effective strategies for implementation available and under study at Duke University
Process for Developing SCD Guidelines • NHLBI evidence based guidelines • Agency for Health Research and Quality commissioned systematic reviews of available evidence for clinical management • Expert panel convened to review the evidence and to hear synthesis of evidence from other experts and to hear affected individuals and families report on their experiences • Panel authored guidelines that were opened to public comment, then finalized
Barriers to Guideline Implementation • Institutional and broader priorities • Resources • Policies, e.g. opioid prescribing • Evidence base • Provider knowledge of, comfort with implementation • Unconscious bias • Lack of cohesion among stakeholders to present consistent message
Implementation at Institutional Level • Institutional Quality office may be place to start, but also ED or Sickle Cell Center • Stakeholders bring concern that institution not providing or improving health care consistent with their goal and mission – quality and safety • Multidisciplinary team establishes process for implementation • Distill guidelines for care providers
Implementation at Institutional Level • Establish baseline of current metrics • Operationalize strategies for implementation • Order sets, preferably in EHR • Note templates • Partner on quality improvement initiatives • QI models and processes look different in different settings, but there are requirements for Performance Improvement activities • Intensive and ongoing education about the guidelines
Multidisciplinary Team • Individuals with SCD/Family Members • Evidence Based Medicine/Implementation specialist • Hematologist • Hospitalist • Outpatient Family Medicine • Anesthesiology/Palliative Care/Pain specialist • Informatics • Pharmacy • Nursing
Metrics and Outcomes • Are the guidelines being used? • Time to first dose of analgesia • Time to second and third doses • Pain score • Medications used/dosing • Outcomes • Length of stay • Readmissions • Patient experience/satisfaction • Acute chest syndrome
Example: BCHO Pain Management Guideline Implementation • Team of ED and Sickle Cell Center staff began to work on revising existing SCD pain management guidelines • Baseline chart reviews to document timing of assessment and treatment in ED • Process mapping to identify barriers and facilitators to timely and appropriate management • Received support from the HRSA Sickle Cell Disease Treatment Demonstration Program • Created nursing driven order set on paper then in HER • ED Fellow major champion
Metrics and Outcomes • Time to first dose of analgesic • Percent of patients who receive 1st pain assessment within 30 minutes of triage • Percent of patients who are reassessed within 30 minutes of 1st analgesic dose • Percent of ED staff (MD and nursing) trained on SCD pain management guidelines • Length of stay in ED • Percent admitted/discharged home • Patient/family satisfaction • Improvement in pain scores
Minutes • Monthly Average • --- Upper and lower control limits (3 standard deviations from mean) • - Mean of monthly averages Treadwell et al J Clin Outcomes Manage 2014;21:62-70
Preparation • Create Awareness and Interest • Build Knowledge and Commitment • Pursue Integration and Sustained Use Implementing Guidelines into Practice • Promote Action and Adoption • Evaluate Cullen, Adams J Nurs Admin 2012; 42: 222-30
Facilitators to Guideline Implementation • Champions • Stakeholder advocacy • Data – risk management, financial • Organizational priorities • Philosophy of care • Ongoing awareness and education • Staff meetings, electronic health record, intranet, in-person trainings
Take-Aways • Existence of guidelines not enough, nor is requirement that guidelines be implemented • Settings vary in barriers and facilitators to implementation • Barriers, facilitators, metrics must be assessed initially • As stakeholders, define your goals, role in the process • Identify champions, owners of process • Operationalization requires diverse teams, particularly nursing
Take-Aways • Ongoing evaluation, tracking of metrics and outcomes • Look for unanticipated negative consequences • Ongoing education absolutely essential • Health disparities contributing to suboptimal pain management cannot be ignored
Evaluate and plan again • Using what resources? • What will be done? • By whom? Action Plan for Guideline Implementation in Your Institution • By when? Advocating for Change Community Toolbox 2018 ctb.ku.edu
Resources • Emergency Department Sickle Cell Care Coalition acep.org/by-medical-focus/hematology/sickle-cell/resources/ • Improving Sickle Cell Care in North Carolina sickleaware.nursing.duke.edu • American Society Clinical Practice Guidelines hematology.org/Clinicians/Guidelines-Quality/Guidelines • NHLBI Evidence Based Management of Sickle Cell Disease nhlbi.nih.gov • SCD Managing Acute Episodes in Hospital nice.org.uk/guidance/cg143