1. Sickle-cell disease By: Adam Clark and Stephanie Fuqua

2. Inheritance • Recessive in parents • Two copies are altered • They combine

3. Symptoms • Painful episodes • Chronic anemia • Serious infections • Damage to organs

4. Punnet Square

5. Sickle-cell anemia in children • Both parents affected • Can be passed onto children

6. Statistics • 72,000 cases in the U.S • 2,000,000 Carriers • 1 in 500 African-Americans born with disease

7. Diagnosis • Early diagnosis critical • Blood tests at birth

8. Treatment • Bone marrow transplant • Medicine for pain • Immunizations • Hydroxyurea

9. Life Expectancy • Over 50 years with proper treatment

10. Causes of Death • Stroke • Heart attack • Kidney or liver failure • Bacterial Infection

11. Living with Sickle Cell • Painkillers • Narcotics • Therapy -relaxation -Hydration therapy • Blood transfusions

12. Help with Sickle Cell