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Explore the metabolic characteristics of glucose and methionine uptake in cells represented as mmol per gCDW per hour. Understand the complex metabolic pathways involved through key intermediates such as RU5P, G6P, and XU5P. Analyze the impact of oxygen consumption and carbon dioxide generation. Compare key metabolites like F6P, E4P, and GAP, highlighting the role of mitochondria and cytosol in the process.
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Met uptake rate [mmol (gCDW·h)1] Glc uptake rate [mmol (gCDW·h)1] MET (E) GLC (E) RU5P MET G6P XU5P XU5P R5P ½O2 + H2O FORM CO2 F6P E4P GAP DHA GAP S7P ACCOA PYR ACCOA Mitochondria Cytosol OAA CIT MAL AKG BIOMASS NADH NAD