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This study investigates the effects of various concentrations of ErPC on the viability of T98G cells subjected to ionizing radiation (IR). Cells were treated with ErPC at concentrations of 0, 12.5, 25, 50, and 100 µM, and then exposed to doses of 0, 5, and 10 Gy of radiation. Viability was assessed at 24, 48, and 72 hours post-treatment. The results demonstrate how ErPC modulates cell viability in response to IR exposure, providing insights into potential therapeutic applications in cancer treatment.
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control 10Gy 0 µM ErPC 0 µM ErPC 100 12.5 µM ErPC 12.5 µM ErPC 80 25 µM ErPC 25 µM ErPC 50 µM ErPC 50 µM ErPC 60 viable cells [%] 40 20 50µM ErPC 10Gy + 50µM ErPC 0 10 0 2.5 5 7.5 2.5Gy 100 100 80 80 0 µM ErPC 60 60 12.5 µM ErPC viable cells [%] viable cells [%] 25 µM ErPC 40 40 50 µM ErPC 20 20 0 0 0 24 48 72 0 24 48 72 time [h] time [h] A B T98G 48h IR [Gy] D C 10Gy
