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2012 9826 MOESM1 ESM

Supplementary Fig. 1. Plasma concentration of ONO-2921 in rats after intravenous administration of ONO-2921 SD2 suspension. The amount of ONO-2921 was determined by HPLC as described in Materials and Methods section. Each value represents the mean ± S.E. (n=3).

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2012 9826 MOESM1 ESM

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  1. Supplementary Fig. 1. Plasma concentration of ONO-2921 in rats after intravenous administration of ONO-2921 SD2 suspension. The amount of ONO-2921 was determined by HPLC as described in Materials and Methods section. Each value represents the mean ± S.E. (n=3).

  2. Supplementary Fig. 2. Solubility of ONO-2921 in the presence of increasing concentration of Malt-β-CD. ONO-2921 was mixed with Malt-β-CD solution and then the mixture was incubated overnight. ONO-2921 was determined by HPLC method as described in Materials and Methods section. Each value represents the mean ± S.D. (n=3).

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