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Penggolongan obat

JURUSAN FARMASI FKIK UNIVERSITAS JENDERAL SOEDIRMAN. Penggolongan obat. Oleh : Hendri Wasito, S. Farm., Apt. Penggolongan obat secara umum. 1. Berdasar Efek Biologis Analgesics, anti-asthmatics, antipsychotics, etc . 2 .Berdasarkan struktur kimianya Penicillins , opiates

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Penggolongan obat

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  1. JURUSAN FARMASI FKIK UNIVERSITAS JENDERAL SOEDIRMAN Penggolongan obat Oleh : Hendri Wasito, S. Farm., Apt.

  2. Penggolonganobatsecaraumum 1.BerdasarEfekBiologis • Analgesics, anti-asthmatics, antipsychotics, etc. 2.Berdasarkan strukturkimianya • Penicillins, opiates • Functions similar or different 3.Berdasarkansistemtargetnya • Antihistamines • Affect a target system (synthesis, release, receptor) 4.Berdasarkantempattargetnya • Anticholinesterases (inhibit acetylcholinesterase in CNS) • Target enzyme or receptor

  3. Penggolonganobatberdasarsumbernya • Obatalamiah • obat yang berasaldarialam (tanaman ,hewan, atau mineral) • Contoh : kuinin, atropin, hormon, belerang, KBr. • Obatsemisintetik • obathasilsintesisdenganbahandasardarialam • Cotoh : kodeindarimorfin, progesterondaridiosgenin • Obatsintetikmurni • obatdarihasilsintesis yang bahandasartidakberkhasiatnamunsetelahdisintesismemilikiefekfarmakologitertentu • Contoh : obatantihistamin, diuretik, analgetik-antipiretik, dsb.

  4. Overview of Drugs Status in the Period 1981-2002 V = vaccines B = biologicals NP = natural products NPD = natural product derivatives SNP = synthetics derived from NP S = straight synthetics V B NP NPD SNP S Compiled from : Newman, D. J., Cragg, G. M., and Snader, K. M. (2003) NATURAL PRODUCTS AS SOURCES OF NEW DRUGS OVER THE PERIOD 1981 – 2002. Journal of Natural Products66, 1022-1037.

  5. Digitalis purpurea (Foxglove) and Digitalis lanata … long known for their healthy heart effects … exert a positive inotropic effect on cardiac muscles … treatment for heart failure

  6. Quinidine …bark of Cinchona tree …… anti-arrhythmic drug. Quinine… no cardiac activity … anti-infective … malaria

  7. Penggolonganobatberdasaraktivitasfarmakologis • Obatantiinfeksi • Obatantibiotika • Obatantikanker • Obatantihistamin • Obatdiuretika • Obatpenekansistemsyarafpusat • Obatperangsangsistemsyarafpusat • Obatanalgetik • Obatkardiovaskular • Obatkolinergik • Obatpemblokkolinergik • Obatadrenergik • Obatpemblokadrenergik • Obathormon steroid • Obatantidiabetes oral • Obatanastetiklokal • dsb.

  8. THANKS ... Selamat belajar dan mencari sumber literatur lainnya...

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