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Analysis of Tracheal Response to Acetylcholine: Fmax and Reference Metrics

This study examines tracheal responses to varying concentrations of acetylcholine (ACh), focusing on the maximum force (Fmax) recorded at different dosages. Utilizing the LEPB, REPB, and IPB measurement systems, we analyze responses at 60%, 50%, 40%, 30%, and 20% ACh reference points. This data highlights the trachea's sensitivity to ACh, providing vital insights into respiratory physiology and potential therapeutic interventions in pathophysiological conditions affecting airway reactivity.

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Analysis of Tracheal Response to Acetylcholine: Fmax and Reference Metrics

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  1. 50 40 Fmax (% reference ACh) 30 * 20 * * * 10 0 trachea LEPB REPB IPB trachea LEPB REPB IPB A B 50 40 * Fmax (% reference ACh) 30 * 20 * * 10 0 trachea LEPB REPB IPB C 60 50 40 Fmax (% reference ACh) 30 20 10 0

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