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Gene Expression Analysis of DNA-PKcs and c-Myc in HepG2 and HeLa Cell Lines

This study investigates the expression levels of DNA-PKcs and c-Myc in various human cell lines, including HepG2 and HeLa, under different experimental conditions. We focus on the impact of siRNA treatments on DNA-PKcs, c-Myc, and Ku70 expression, monitored through Western blot analysis. The study aims to elucidate the role of these proteins in cellular responses to treatments involving TCDD and the potential implications for cancer research.

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Gene Expression Analysis of DNA-PKcs and c-Myc in HepG2 and HeLa Cell Lines

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  1. HepG2-NC HepG2-H1 HepG2-H3 B A HeLa-NC HeLa-H1 M059K M059J DNA-PKcs c-Myc -actin DNA-PKcs c-Myc -actin DNA-PKcs c-Myc -actin E D AT5BIVA Control siRMA DNA-PKcs siRNA L02/TCDD-NC L02/TCDD-H1 HFC TCDD 0 0.01 0.1 (pM) DNA-PKcs c-Myc Ku70 -actin DNA-PKcs c-Myc Ku70 -actin C F DNA-PKcs c-Myc Ku70 -actin

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