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Understanding Bone Formation and Growth: Ossification, Nutritional Requirements, and Conditions

This chapter explores the complex process of bone formation and growth, beginning at six weeks after fertilization and continuing through adolescence, with some growth lasting until age 25. It details two main types of ossification: intramembranous and endochondral. Nutritional requirements for healthy bone development, including calcium and vitamin D, are emphasized. The chapter also addresses bone-related conditions such as rickets and scurvy, highlighting the importance of vitamins A, C, and D in maintaining strong bones.

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Understanding Bone Formation and Growth: Ossification, Nutritional Requirements, and Conditions

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  1. Chapter 6.2: Skeletal System

  2. Bone Formation and Growth • Begins 6 weeks after fertilization • Continues throughout adolescence • Can continue until 25 • Ossification—replacing tissue with bone

  3. Intramembranous Ossification • Differentiate into bones • Flat bones form this way

  4. Figure 6.4

  5. Endochondral Ossification • Most bones formed this way • Forms from hyaline cartilage models • Cartilage starts to calcify • Osteoblasts cover shaft • Blood vessels penetrate the cartilage • Bone of shaft thickens

  6. Figure 6.4

  7. Bone Growth • Women—stop by 18 • Men—stop by 20

  8. Requirements for Bone Growth • Calcium • Comes from mom pre-birth • Mom loses bone mass while pregnant

  9. Requirements cont… • Vitamin D3 • Through vitamins or UV rays • Processed by liver • Allows calcium and phosphate to be absorbed

  10. Requirements cont… • Rickets • Soft and bendable bones in kids • Result of vitamin D deficiency • Bowlegged appearance

  11. Requirements cont… • Vitamins A and C • Scurvy—lack of vitamin C • Decreased osteoblast activity • Weak and brittle bones

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