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This chapter explores the complex process of bone formation and growth, beginning at six weeks after fertilization and continuing through adolescence, with some growth lasting until age 25. It details two main types of ossification: intramembranous and endochondral. Nutritional requirements for healthy bone development, including calcium and vitamin D, are emphasized. The chapter also addresses bone-related conditions such as rickets and scurvy, highlighting the importance of vitamins A, C, and D in maintaining strong bones.
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Bone Formation and Growth • Begins 6 weeks after fertilization • Continues throughout adolescence • Can continue until 25 • Ossification—replacing tissue with bone
Intramembranous Ossification • Differentiate into bones • Flat bones form this way
Endochondral Ossification • Most bones formed this way • Forms from hyaline cartilage models • Cartilage starts to calcify • Osteoblasts cover shaft • Blood vessels penetrate the cartilage • Bone of shaft thickens
Bone Growth • Women—stop by 18 • Men—stop by 20
Requirements for Bone Growth • Calcium • Comes from mom pre-birth • Mom loses bone mass while pregnant
Requirements cont… • Vitamin D3 • Through vitamins or UV rays • Processed by liver • Allows calcium and phosphate to be absorbed
Requirements cont… • Rickets • Soft and bendable bones in kids • Result of vitamin D deficiency • Bowlegged appearance
Requirements cont… • Vitamins A and C • Scurvy—lack of vitamin C • Decreased osteoblast activity • Weak and brittle bones