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This study investigates the mitochondrial DNA (mtDNA) content across multiple treatment groups involving uninfected controls, BFA, HAART, and their combinations. We measured mtDNA levels as ND2/18SrRNA ratios, highlighting significant differences with p-values < 0.01 and < 0.05 in relation to controls. Our findings suggest that different therapeutic regimens influence mitochondrial dynamics, warranting further exploration of their implications for cellular metabolism and health outcomes in treated populations.
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Uninfected controls BFA-HAART- BFA-HAART+ BFA+ HAART- BFA+ HAART+ Supplemental Digital Content 3 MITOCHONDRIAL DNA CONTENT mtDNA /nDNA (ND2/18SrRNA) ** * *p=<0.01 with respect to controls ** p<0.05 with respect to controls