1 / 30

Functions of Bone (Osseous Tissue)

Delve into the world of bone tissue, understanding its role in structural support, protection, storage of minerals and lipids, blood cell production, body movement, and detoxification. Uncover the constituents of bone, both organic and inorganic components, specialized bone cells, and the hormonal control that regulates bone tissue. Learn about the different types of ossification, bone growth processes, and bone remodeling. Discover common disorders of bone tissue such as osteopenia, osteomalacia, osteoma, and osteoporosis. Gain insights into the factors that contribute to these conditions, from hormonal imbalances to mineral deficiencies.

janine
Télécharger la présentation

Functions of Bone (Osseous Tissue)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Functions of Bone (Osseous Tissue) • Structural Support: • Protection: • Storage: 1) minerals and 2) lipids • Blood Cell Production: • Body Movement: • Detoxification:

  2. Constituents of Bone Organic (~1/3) Calcium Hydroxyappitite Ca3(PO4)2.(OH)2 80% Collagen Inorganic (~2/3) Specialized Bone Cells Calcuim Carbonate CaCO3 15% Glycosaminoglycans (GAGs) Other Minerals: Mg, SO4, Na, K 5% Flexibility! Rigidity!

  3. Compact Bone

  4. Specialized Bone Cells

  5. Hormonal Control of Bone Tissue Human Growth Hormone (hGH): (Pituitary gland) Thyroxine: (Thyroid gland) Stimulate Osteoblasts Sex Hormones: (estrogen, progesterone, testosterone) (Ovaries and Testes) Calcitonin: Inhibits Osteoclasts (Thyroid gland) Parathyroid Hormone: (Parathyroid gland) Stimulates Osteoclasts Increases Ca2+ absorption from intestine, ↓ Ca2+ in urine. Calcitriol: (Skin and kidneys)

  6. 2 Types of Ossification 1. Intramembranous Ossification mesoderm Mesenchymal cells Osteoprogenitor cells osteoblast Osteocytes in bone tissue

  7. 2. ENDOCHONRAL OSSIFICATION starts as a cartilage model of bone

  8. Appositional Bone Growth Bone Remodeling: Depositing and removing bone tissue!

  9. Fractures Simple (Closed): Compound (Open):

  10. Disorders of Bone Tissue • Osteopenia: A reduction in bone mass with age. • Osteomalacia (‘rickets’ in children): Defective mineralization of bone, resulting in too much flexibility, bone cannot bear weight sufficiently. • Osteoma: Cancer of bone tissue (uncontrolled bone growth, a malignant tumor = cancer).

  11. Osteoporosis: A significant reduction in bone mass that impairs function. From too little mineralization of bones for these reasons: • Decrease in hormone levels, e.g., loss of estrogen at menopause – decreases efficiency of calcium absorption. 2) deficiency of minerals in youth, thus too little to begin with. 3) imbalance of activity of osteoblasts and osteoclasts.

More Related