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GLOMERULAR DISEASES

NEPHROTIC SYNDROME NEPHRITIC SYNDROME Proteinuria ( >3.5g/24h) Haematuria Hypoalbuminaemia (<30g/L) Hypertension Oedema Oliguria (Oedema) Minimal change nephropathy Post-infective GN Membranous nephropathy IgA nephropathy.

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GLOMERULAR DISEASES

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  1. NEPHROTIC SYNDROME NEPHRITIC SYNDROME Proteinuria ( >3.5g/24h) Haematuria Hypoalbuminaemia (<30g/L) Hypertension Oedema Oliguria (Oedema) Minimal change nephropathy Post-infective GN Membranous nephropathy IgA nephropathy Histology of the glomerulus GLOMERULAR DISEASES • Diabetic nephropathy • Screen for microalbuminuria (ACR > 2.5 M, >3.5 F) • Thickened GBM Mesangial expansion Nodules • Slow progression with good control and ACEi • Investigations in suspected glomerular diseases • Make sure you understand why these are required • Not all done every time • Bedside – urine dip • Bloods – FBC, U&E, CRP, ESR, ANA, ANCA, dsDNA, complement, anti-GBM, ASOT • Lab tests – urine microscopy (casts), 24h protein, ACR, throat/skin swabs • Renal USS +/- renal biopsy

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