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Thyroid part 2. Hypothyroidism. Hypothyroidism. Definition i TH Pathophysiology Primary hypothyroidism Thyroid fails to produce enough TH Secondary Hypothyroidism i stimulation Thyroid (pituitary or hypothalmus). Hypothyroidism. Etiology Primary Congenital I deficiency
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Thyroid part 2 Hypothyroidism
Hypothyroidism Definition • i TH Pathophysiology • Primary hypothyroidism • Thyroid fails to produce enough TH • Secondary Hypothyroidism • i stimulation Thyroid (pituitary or hypothalmus)
Hypothyroidism Etiology • Primary • Congenital • I deficiency • Auto-immune • Thyroidectomy • Secondary • Pituitary / hypothalamus
Hypothyroidism S&S • Think ______ • Slow
HypothyroidismS&S Neurology • Slow mentation • Slurred speech Affect • Lethargy • depression
HypothyroidismS&S Cardiovascular • Bradycardia Gastro-intestinal • Constipation • Weight gain • Appetite loss
HypothyroidismS&S Muscular-skeletal • Clumsy slow movements • Fatigue • Cold intolerance • Dull facial expression
HypothyroidismS&S Skin • Dry, pale • Hair dry • Thick lips • Puffy eyes
Hypothyroidism Cretinism • Rare in the US • Congenital condition d/t i TH physical & mental retardation • 18yr old
Hypothyroidism Hashimoto’s thyroiditis • Most common adult hypothyroidism • Auto-immune • Female > male • Age: • 30-50
By definition hypothyroidism means what? T3/T4 i HypothyroidismDiagnostic Tests
HypothyroidismDiagnostic Tests • By definition primary hypothyroidism means what? (where is the problem – what is causing the problem?) • Thyroid • i T3/T4 • In primary hypothyroidism, is the pituitary gland working correctly? • Yes
If the pituitary gland is working correctly and there is an i T3/T4 level, what will the Pituitary gland do with the TSH level? HypothyroidismDiagnostic Tests
By definition hypothyroidism means what? T3/T4 i HypothyroidismDiagnostic Tests
HypothyroidismDiagnostic Tests • By definition secondary hypothyroidism means what? (where is the problem – what is causing the problem?) • Pituitary gland • i TSH • i T3/T4
By definition secondary hyporthyroidism means what? (where is the problem – what is causing the problem?) Pituitary gland i TSH i T3/T4 HypothyroidismDiagnostic Tests
HypothyroidismMedical Treatment Rx / life time • Thyroid (Armour thyroid) • Natural form • Levothyroxine sodium / Levothroid, Synthroid • Synthetic • Time of dose • AM • Monitor __________system • C/V • Gradually h meds • takes 2 wks to know full affect • Blood level monitoring • Annually • Know S&S and report
HypothyroidismMedical Treatment Diet • Fiber • h • Protein • h • Fluids • h • Calories • i • Avoid food h in I (interferes with meds)
Avoid food h in I • Kelp • Shellfish • Iodized salt • Cabbage • Turnips • Pears • Peaches
HypothyroidismNursing management • Rest • Space • Skin • Protect • Diet • Adjust
Severe Hypothyroid State Myxedema • Definition • Advanced hypothyroidism • Etiology • Iodine deficiency • Atrophy of thyroid • Surgery • Destruction of thyroid by I 131
Hypothyroidism SevereMyxedema Characteristics • Growing puffiness & sogginess of the skin • Dry, waxy edema (non-pitting) • Abnormal deposits of mucin in the skin • Distinctive facial changes
Hypothyroidism Severe Myxedema Coma • Met. Rate drops so low life threatened • Temperature • < 95 F • Blood pressure • i • Glucose • i • Mental function • i
Hypothyroidism Severe Myxedema Coma • Death d/t… • Respiratory Failure
Goiters Definition • Enlarged thyroid Pathophysiology
Review! • What hormone causes the thyroid to grow? • TSH • What hormonal change causes goiters? • h TSH
Goiters Definition • Enlarged thyroid Pathophysiology • h TSH levels goiters Etiology • i TH levels • i Iodine • PG
Goiters • Endemic goiter • Caused by environmental factors • i iodine
Goiters • Are goiters assoc. with • Hyperthyroidism • YES! • Hypothyroidism • YES! • Euthyroid state • YES! • All of the above
Goiters Goitrogens • Suppress thyroid function • Broccoli • Cauliflower • Cabbage • Turnips • Sulfonamide • Lithium • Salicylates
Goiters S&S • Enlarged thyroid Complications • May interfere with • Respiration • Swallowing
Goiters Nursing Management • Diet • Limit goitrogens • Assess • Breathing • Stridor • Swallowing • Palpate???? • NO!
Cancer of the Thyroid gland Etiology • Rare • F>M • Thyroid hyperplasia • Radiation • Iodine deficiency
Cancer of the Thyroid gland • #1 S&S • Nodule on thyroid • Hard • Painless
Cancer of the Thyroid gland S&S • Difficulty swallowing or breathing • Changes in voice • Lab values • Normal TH levels
Cancer of the Thyroid gland Diagnostic Tests • Thyroid scan • Shows “cold” spot • Area that did not take up radioactive material • Indicates malignancy • Biopsy • Confirms diagnosis
Cancer of the Thyroid gland Medical Management • Thyroidectomy • Partial • Total • Chemotherapy
Cancer of the Thyroid gland Nursing Management- thyroidectomy • Pre-op • Euthyroid state • Verify meds taken
Cancer of the Thyroid gland Nursing Management- thyroidectomy • Post-op • Vital Signs • i BP & h Pulse = • Shock d/t hemorrhaging • h Pulse h fever h BP = • Thyrotoxic crisis
Cancer of the Thyroid gland Nursing Management- thyroidectomy • Post-op • Check hemohaggin • back of neck for pooling blood • Check for S&S of dyspnea or resp distress • Check speech • Semi-fowlers position
Cancer of the Thyroid gland Nursing Management- thyroidectomy • Post-op • Activity • Support neck • Monitor for Tetany • Continuous tonic spasm • Tracheostomy set at bed side • Resp. obstruction • Diet Changes (esp. if hyperthyroidism) Tetany Tetanus
Thyroidectomy Complications • Thyrotoxic crisis • D/t manipulation of thyroid during surgery • release large amount of TH
ThyroidectomyComplications Tetany • D/T low Ca levels • Characterized by • Fingers & perioral area tingling • Muscle spasm • Twitching • Cardiac Dysrhythmias • Etiology • D/t removal of parathyroid gland • Treatment • IV Calcium gluconate • Breath into a paper bag • mild acidosis • h Calcium in blood