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Derivatives of Aromatic compound

Derivatives of Aromatic compound. Kh.Sadique Faisal Asst. Lecturer Northern University Bangladesh. Lornoxicam.

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Derivatives of Aromatic compound

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  1. Derivatives of Aromatic compound Kh.Sadique Faisal Asst. Lecturer Northern University Bangladesh

  2. Lornoxicam • Lornoxicam (INN, or chlortenoxicam; trade name Xefo, among others) is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations. It is a thiophene derivatives. • Lornoxicam is used for the treatment of various types of pain, especially resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica, and other inflammations

  3. Piroxicam • Piroxicam is a non-steroidal anti-inflammatory drug of the oxicam class used to relieve the symptoms of rheumatoid and osteoarthritis, primary dysmenorrhoea, postoperative pain; and act as an analgesic, especially where there is an inflammatory component • It is also used in veterinary medicine to treat certain neoplasias expressing cyclooxygenase(COX) receptors, such as bladder, colon, and prostate cancers.

  4. Pyridine derivatives • Tripelennamine Tripelennamine (sold as Pyribenzamine by Novartis) is a psychoactive drug and member of the pyridine and ethylenediamine classes that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitus and urticaria, but is now less common as it has been replaced by newer antihistamines. Cough medicine of the general formula tripelennamine + codeine/dihydrocodine/hydrocodone ± expectorant ± decongestant(s) is quite popular where available

  5. Pyridine derivatives • Niacin (also known as vitamin B3, nicotinic acid and vitamin PP) is an organic compound with the formula C6H5NO2 and, depending on the definition used, one of the forty to eighty essential human nutrients. • Niacin is one of five vitamins (when lacking in human diet) associated with a pandemic deficiency disease: niacin deficiency (pellagra), vitamin C deficiency (scurvy), thiamin deficiency (beriberi), vitamin D deficiency (rickets), vitamin A deficiency (night blindness and other symptoms). Niacin has been used for over 50 years to increase levels of HDL in the blood and has been found to modestly decrease the risk of cardiovascular events in a number of controlled human trials

  6. Pyridine derivatives • Pyridoxine • Pyridoxine is one of the compounds that can be called vitamin B6,along with pyridoxal and pyridoxamine. It differs from pyridoxamine by the substituent at the '4' position. Its hydrochloride salt pyridoxine hydrochloride is often used. Pyridoxine is given to patients taking Isoniazid (INH) to combat the toxic side effects of the drug. It is given 10–50 mg/day to patients on to prevent peripheral neuropathy and CNS effects that are associated with the use of INH.

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