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Multiple Sclerosis

Multiple Sclerosis. By Birger Flønæs & Christoffer Brovold. Introduction. Twice as common among females 7000-8000 diagnosed patients in Norway 250-350 new patients every year Makes Norway one of the countries in the world with highest relative number of MS patients. Epidemiology. Overview.

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Multiple Sclerosis

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  1. Multiple Sclerosis • By Birger Flønæs & Christoffer Brovold

  2. Introduction • Twice as common among females • 7000-8000 diagnosed patients in Norway • 250-350 new patients every year • Makes Norway one of the countries in the world with highest relative number of MS patients.

  3. Epidemiology

  4. Overview

  5. Pathophysiology • Auto-immune disease • BBB breakdown • Mainly CNS is affected • Destroys oligodendrocytes

  6. Classification

  7. Symptoms • Numbness • Visual disturbances • Reduced motor function • Paralysis of extremities • Reduced fine motor skills • Chronic fatigue

  8. Consequences for the patient • Spasms • Pain - strain, nervous, sciatica • Paralysis • Depressions • Cognitive impairment • Loss of sensitivity, tingling, muscle weakness, difficulties in moving and coordination, problems in speech/swallowing, visual problems etc.

  9. Etiology • Combination of genetic, environmental • Not considered hereditary, but genetic variations increase risk • Decreased sunlight exposure --> vitamin D deficiency • Stress • Smoking

  10. Treatment • No curative treatment • beta-interferons - 18-38% reduction in rate of MS relapses • Synthetic myelin basic protein - 1/3 reduction • Immuno-suppressive medicines - progressive MS • Cannabis • Botox

  11. Sources • Wikipedia • www.ms.no

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