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Biozip Suture Group 24 Katie Good and Emily Schaefer

This project aims to create a bioabsorbable zip-tie suture that allows for easy application of tension in one direction, maintaining the suture securely tied during deep tissue procedures. The current techniques for suturing in confined areas are challenging and compromise suture integrity. Our approach includes using shape memory polymers and optimizing material selection. Future work involves testing our designs and finding a manufacturer for production.

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Biozip Suture Group 24 Katie Good and Emily Schaefer

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  1. Biozip SutureGroup 24Katie Good and Emily Schaefer Advisors: Bruce Beyer, M.D. Paul King, Ph.D.

  2. Problem Statement • Requirement • Bioabsorbable zip-tie suture • Performance Criteria • Unidirectional Tension • Maintain suture tied and tight • Primary Objective • Create suture allowing tactility and ease during deep tissue procedures

  3. Quality Function Deployment

  4. Current Technique • Current sutures - application of tension in opposite directions • Gynecological procedures - confined areas • Difficult to apply tension • Suture integrity compromised

  5. Suture Tying http://www.brooksidepress.org/Products/Suturing_entrance.htm

  6. Laparoscopic Technique • Advantages • Minimally invasive • Requires tension in one direction • Disadvantages • More complex system • Not widely used

  7. Endoscopic Suturing System http://paresurgical.com/procedure.htm

  8. Our Approach • Require tension in one direction • Noose type knot • Shape memory http://www.realknots.com/knots/noose.htm Movie clip of a shape memory polymer (scroll to bottom)

  9. Materials • Monofilament vs. Braided • Tensile Strength (0-gauge) • Polyglactin 910 • (Vicryl) ~ 95 N • Polyglycolic Acid • (Dexon) ~85 N • Polyglyconate • (Maxon) ~106 N • Polydioxanone • (PDS) ~82 N

  10. Current Status • Meeting with Dr. Beyer Monday 29th to • Discuss progress • Ask surgery specific questions/concerns • Continue literature search • Meet with Dr. Shastri to discuss shape memory sutures

  11. Future Work • Select a material to optimize design • Testing our designs in a virtual or real life simulator • Find a manufacturer who produces material to get a quote for our design

  12. References • Bourne, R.B., MD, FRCSC, Bitar, H. MD, Andreae, P.R., BSC, Martin L.M., MB, BS, Finlay, J.B., PhD, & Marquis, F., MD FRCSC (1988). In-vivo comparison of four absorbable sutures: Vicryl, Dexon Plus, Maxon, and PDS. The Canadian Journal of Surgery, 31(1), 43-45. • von Fraunhofer, J. A., Storey, R. S., Stone, I. K., & Masterson, B. J. (1985). Tensile strength of suture materials. Journal of Biomedical Materials Research, 19(5), 595-600.

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