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Innovative Suture Design for Gynecological Procedures: Enhancing Closure Techniques

The proposed research focuses on an advanced suture design optimized for gynecological procedures that typically occur in confined areas, where applying tension can be challenging. Our innovative solution aims to provide a bioabsorbable suture with unidirectional tension and strong integrity, facilitating simple closure procedures. With annual surgeries like C-sections and hysterectomies in mind, the improved suture design addresses issues of compromised integrity and reduces surgery time, ultimately enhancing patient outcomes and minimizing infection risks.

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Innovative Suture Design for Gynecological Procedures: Enhancing Closure Techniques

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  1. Biozip SutureGroup 24Katie Good and Emily Schaefer Advisors: Bruce Beyer, M.D. Paul King, Ph.D.

  2. Problem Statement • Gynecological procedures - confined areas • Difficult to apply tension • Suture integrity compromised • Alternative method for closing tissue or pedicles • Require tension in one direction

  3. Desired Qualities • Bioabsorbable • Tensile strength • 80 – 100 N • Degradation time • 3 -4 weeks • Unidirectional Tension • Maintain suture integrity • Simple closure procedure

  4. Design Significance • C-section - 1.2 Million surgeries/year • Hysterectomy - 600,000 surgeries/year • Improved suture design will • Decrease surgery time and therefore potential for infection • Easier closure procedure • Greater confidence in suture integrity

  5. Competing Technologies • Traditional suture • tension in opposite directions, form knots • Laparoscopic technique • Quik-Stitch® • LIGA – CLIPS (Ethicon) • Metal surgical clips • Electrocautery • Sealing pedicles http://www.paresurgical.com

  6. Twist Tie Approach • Vicryl • 0 and 2 gauge • Braided • Coated • Dexon • 3 gauge • Braided • Uncoated Clamp & Fuse

  7. Budget • Hemostat • 7.25” ~ $21.00 • Suture material • Vicryl 0 (qty 6) ~ $1.57 ea • Vircyl 2-0 (qty 6) ~ $1.50 ea • Dexon 3-0 (qty 3) ~ $15.96 ea • Total ~ $87.30 • Heated tweezers ~ $209

  8. Fusing Sutures • Dexon • did not fuse • Vicryl • 3 sutures per trial • Trials

  9. Testing Our Sutures • Instron Tensiometer • BlueHill software • Ideal for < 2kN • 0.4% accuracy • Output • Tensile strength • Elongation • Breaking Point • Located in VUMC SDRCC http://www.instron.us/wa/products/universal_material/5840.aspx

  10. Heating Element • Heated Tweezers • Wax Connections • Pedal controls power to tweezers • No specific temperature listed http://www.waxconnections.com/Page11.html

  11. Current Status • Purchased sutures from Hospital Supply • Fused Vicryl sutures w. hair straightener • Meeting – Dr. DasGupta on Thursday • Learn to use tensiometer • Test samples • Meet with Dr. Beyer • Ask to tie sutures for comparison testing

  12. Future Work • Research other heating element options • Research current surgical heating techniques • Dr. Beyer test procedure for ease of application • Paper and poster

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