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Exploring New Research Areas in Youth Health Valuation Models: Latest Insights from EQ-5D-Y Development

Discover the latest research from EuroQol Group in the development of the EQ-5D-Y youth version. Dive into ongoing studies on disease-specific adaptations and additional dimensions, like cognition. Explore how to value health states for children, parents, and the general public. Uncover insights on coping skills in children and examine if values differ across different age groups. Gain valuable information on applying the Time Trade-Off method for children's health states. Delve into the complexities of modeling TTO values for conditions like psoriasis. Join the discussion on expanding dimensions beyond the traditional EQ-5D framework.

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Exploring New Research Areas in Youth Health Valuation Models: Latest Insights from EQ-5D-Y Development

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  1. New and ongoing areas of research In the EuroQol Group

  2. New research • International 5L valuation • Discussed already • EQ-5D-Y • Youth version • Disease specific adaptations • ‘Bolt on’ additional dimensions

  3. EQ-5D-Y: Youth

  4. EQ-5D-Y: Youth • Translations • Available in more than 20 languages • Youth between 7-12 years • Proxy versions • In development

  5. Administration seems OK

  6. But not yet a value set • How should value the health states • Children? • Parents? • The general public? • How do you include: • Development backlog? • The remarkable coping skills children?

  7. Are values different • Do we value health states different? • For ourselves • For someone other like ourselves • For a 10-year child • New paper of the 2012 Meeting

  8. Values for children 10% lower

  9. Small number of health states Still VAS Does this also apply for TTO? Complication: How to apply TTO for health states of children? Descriptive system EQ-5d-Y is different! Feedback from the 2012 meeting

  10. Bolt-on • Do we miss dimensions? • In the past: EQ-6D • Mobility; • Daily activity and self care; • Work performance • Family and leisure performance • Pain/discomfort • Present mood • First attempts • EQ-5D+cog: addition of cognition?

  11. EQ-5D+cog • Used in DALY WHO project • Cognition was recognized as important • Lot of discussion • Is it necessary? • Who is making the value set? • An unofficial set exist • Based on mapping DALY project • Is used… • But gives confusion • No official status

  12. Why not other dimensions? • Developed already • Psoriasis • Vision

  13. VF-14 by Visual acuity in macular degeneration

  14. EQ-5D by Visual acuity in macular degeneration

  15. Evidence on EQ-5D: some examples Hearing Schizophrenia Bipolar disorder Vision Depression and anxiety Some cancers Skin Personality disorder

  16. Psoriasis

  17. Estimation of utilities • Used standard EQ-5D-3L TTO protocol • General public interviews in UK only • N = 300 • Sub-set of 49 states were included using orthogonal design

  18. Results • OLS and random effects models estimated • Interaction terms; collapsing levels • Both dimensions have a significant impact • Some inconsistencies in the data • The largest gap is between level 3 and 4 (moderate and severe)

  19. Modeling TTO values Psoriasis

  20. Discussion 2012 meeting • No real problem when seen as pilot • Convenience sample • TTO not standardised • Methodological complications • Things get complicated for responders fast • 223451 versus 122345 • Cognition overload • 57 = 78.125 health states • Similar values for 4th and 5th levels • Modeling stressed to the limit?

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