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Understanding Nucleotides and DNA Replication: Key Concepts and Processes

This lesson focuses on the structure of nucleotides and the intricacies of DNA replication. Students are encouraged to draw and label a nucleotide to reinforce their understanding. DNA replication, occurring within the nucleus, involves complex processes including uncoiling, unzipping, and the role of enzymes like DNA polymerase. Furthermore, the importance of complementary base pairing and the concept of semi-conservative replication are highlighted. Dive into these essential topics and explore the mechanisms that ensure accurate DNA copying.

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Understanding Nucleotides and DNA Replication: Key Concepts and Processes

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  1. Bell Ringer 10/22/13 Respond to the following in your notes: Draw a nucleotide and label the parts (don’t cheat – see if you remember!) What is the purpose of PCR? (this was in your Ch. 9 HW) Leave the sheets on your desk alone for now – we will look at those in a bit

  2. DNA Replication

  3. DNA Replication • Replication = DNA copies itself exactly • (Occurs within the nucleus) • Any mistake in copying = mutation

  4. A. Basic Facts of DNA Replication 1. Complementary base pairing makes replication possible C - G A - T

  5. A. Basic Facts of DNA Replication 2. One side of DNA molecule is a templatefor making the other side (strand)

  6. B. Process of DNA Replication • Uncoil & unzip DNA molecule • Enzyme (-ase) breaks weakHydrogen Bonds between bases

  7. B. Process of DNA Replication 2. Enzyme brings in complementary N-bases DNA Polymerase

  8. B. Process of DNA Replication 3. New hydrogen bonds form between nitrogenous bases of the template strand and the newly-forming daughter strand. DNA Replication Tutorial http://highered.mcgraw-hill.com/sites/9834092339/student_view0/chapter14/dna_replication.html

  9. C. Semi-conservative replication

  10. DNA vs. RNA - Structure

  11. DNA vs. RNA – Add’tl info

  12. RNA vs. DNA

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