Chew On this. A nurse’s guide to teaching the oncologist averse what to eat and why. Bianca Moses Fall 2012. Cancer Primer. Cancer Primer. Cancer is just:. Cancer Primer. Cancer is just:. Cancer Primer. Cancer is just: a cluster of AWOL cells. Cancer Primer. Cancer is just:
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Chew On this A nurse’s guide to teaching the oncologist averse what to eat and why Bianca Moses Fall 2012
Cancer Primer • Cancer is just: • a cluster of AWOL cells
Cancer Primer • Cancer is just: • a cluster of AWOL cells • that happened to get together one day
Cancer Primer • Cancer is just: • a cluster of AWOL cells • that happened to get together one day
Cancer Primer • Cancer is just: • a cluster of AWOL cells • that happened to get together one day • and decide to re-appropriate real estate from the tissues of your body
Cancer Primer • Cancer is just: • a cluster of AWOL cells • that happened to get together one day • and decide to re-appropriate real estate from the tissues of your body • so that they could establish their own sick cancer commune.
Cancer Primer • Cancer is just: • a cluster of AWOL cells • that happened to get together one day • and decide to re-appropriate real estate from the tissues of your body • so that they could establish their own sick cancer commune.
Cancer Primer • Obviously, these aren’t cells that play by the rules!
Cancer Primer • Obviously, these aren’t cells that play by the rules! • These cancer cells have tempers
Cancer Primer • Obviously, these aren’t cells that play by the rules! • These cancer cells have tempers • and they get pushy
Cancer Primer • Obviously, these aren’t cells that play by the rules! • These cancer cells have tempers • and they get pushy • and they grow into and on top of the polite body cells
Cancer Primer • Obviously, these aren’t cells that play by the rules! • These cancer cells have tempers • and they get pushy • and they grow into and on top of the polite body cells • …with complete disregard for these nice body cell’s personal space bubbles
Cancer Primer • Obviously, these aren’t cells that play by the rules! • These cancer cells have tempers • and they get pushy • and they grow into and on top of the polite body cells • …with complete disregard for these nice body cell’s personal space bubbles
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune • Without vessels, tumors grow no larger than a pea VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Once their numbers become so plentiful that they reach the verge of dying from starvation • They send out chemicals to cause blood vessels to grow directly into their tumor commune • Without vessels, tumors grow no larger than a pea • With vessels, tumors become huge, break off and use those same vessels as highways to metastasize all over the body VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Tumors initiating a blood supply is called ANGIOGENESIS VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor
Cancer Primer • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Travel through vessels to stop tumor from secreting more VEGF Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Travel through vessels to stop tumor from secreting more VEGF Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Travel through vessels to stop tumor from secreting more VEGF Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis • No blood supply = VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Travel through vessels to stop tumor from secreting more VEGF Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis • No blood supply = No TUMOR VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
Block VEGF receptors on intercepting blood vessels Bind to VEGF in circulation preventing receptor binding Travel through vessels to stop tumor from secreting more VEGF Anti-Angiogenesis • Tumors initiating a blood supply is called ANGIOGENESIS • We have found drugs to inhibit and reverse angiogenesis • No blood supply = No TUMOR VEGF: Vascular Epithelial Growth Factor Avastin Itraconazole Carbocyamidotriaole Prolactin TNP-470 CM101 IFN-α Tecogalan Linomide IL-12 Platelet Factor 4 Suramin Lucentis Thrombospondin Angiostatin Endostatin Linomide 2-Methoxyestradiol And many more…
