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Recent findings indicate that parental consanguinity has a significant association with severe phenotypes in patients with common variable immunodeficiency (CVID). This research highlights the genetic factors contributing to the severity of CVID, underscoring the importance of family history in clinical assessments. Understanding the implications of consanguinity can aid in better diagnosis and management strategies for patients affected by CVID, ultimately improving patient outcomes and understanding the underlying immunological mechanisms involved.
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08-07-01 38-01-01 01-60-01 69-01-01 08-12-01 69-78-01 22-01-01 35-01-01 24-06-01 38-01-02 38-01-04 38-01-03 69-34-01 Parental consanguinity is associated with a severe phenotype in common variable immunodeficiency. 70-01-01 01-59-01 05-07-01 01-14-01 01-51-01 01-08-01 04-05-01 01-94-01 23-01-01 Rivoisy et al. J. Clin. Immunol. 69-85-01 70-22-01 69-83-01