1. Long-Term Outcomes of the Boston Type I Keratoprosthesis Jennifer Li, M.D., Mark Greiner, M.D. Ana Carolina Vieira, M.D. Mark Mannis, M.D. University of California, Davis Sacramento, California The authors have no financial interest in the subject matter of this poster.

2. Study Purpose • To evaluate long-term outcomes after placement of Boston type 1 keratoprosthesis • To determine the types and frequency of complications that may develop postoperatively

3. Materials and Methods • A retrospective chart review of all Boston type 1 keratoprosthesis surgeries performed at a single institution (UC Davis) beginning in May, 2004 through January, 2010

4. Boston Keratoprosthesis UC Davis,2004-2010

5. Patient Demographics

6. Preoperative BCVA

7. Preoperative Glaucoma

8. Preoperative versus Postoperative BCVA

9. Postoperative BCVA Changes:Comparing pre-op to final post-op BCVA

10. Postoperative Complications *23 (57.5%) had preoperative glaucoma diagnosis. **7 of 8 GDD erosions required revision and/or removal of device.

11. Retroprosthetic Membrane Periprosthetic Infiltrate Extrusion of Keratoprosthesis Exposed Tube Shunt

12. Conclusions • High percentage of patients have long-term BCVA equal to or better than pre-operative visual acuity • There is a moderately high percentage of patients with long-term complications status post Boston type 1 keratoprosthesis placement • Progression of glaucoma and complications related to glaucoma can be visually devastating • Although many patients may benefit from keratoprosthesis placement, long-term visual prognosis is guarded. • Successful management of these patients requires pre- and post-operative collaboration with glaucoma and vitreoretinal specialists • Further study is needed to determine the best means of managing postoperative glaucoma