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Comparative Anatomy of Digestive Tract: Mucosal Tissue Variations across Tract

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Detailed comparison of mucosal structures in esophagus, stomach, small intestine, and large intestine. Understanding the diversity and similarities in digestive tract tissues.

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Comparative Anatomy of Digestive Tract: Mucosal Tissue Variations across Tract

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  1. Digestive tract

  2. Dark C Taste pore Light C Taste bud

  3. circumvallated papillae（HE） filiform and fungiform papillae（HE）

  4. Foliate papillae-taste bud （HE） Tongue foliate papillae（HE） Taste pore

  5. ● mucous membrane of tongue • Lingual papillae: filiform, fungiform & circumvallated. • Tast bud: dark C, light C & basal C.

  6. General structure of the wall 1.mucosa: • epithelium: • Lamina propria: • Muscularis mucosa: 2.submucosa: 3.Muscularis externa: 4.adventitia:

  7. 4sub mucosa 1Epi. 2lamina propria 4esophageal glands 3 muscula ris mucosa 5inner circular M 6 adven titia 5outer longi tudinal M Esophagus （HE）

  8. epithelium Esophageal gland Esophagus

  9. Esophagus 1.mucosa: ● Epi.: stratified squamous. Non-keratinized ● lamina propria: CT. ● muscularis mucosa: boudles of SMC.longitudinal 2.sbumucosa: esophageal glands, mucous. 3.muscularis: inner circular, outer longitudinal 4.adventitia:fibrosa. • upper1/3:skeletal M. • middle: mixed. • Lower1/3: smooth M.

  10. Stomach

  11. fundus

  12. Stomach • mucosa: • Simple columnar Epi.:surface mucous cell • Lamina propria:gastric pit, gastric glands • Muscularis mucosa: inner circular, outer longitudinal. • submucosa: LCT. • muscularis:inner oblique, middle circular, outer longitudinal. • Adventitia: serosa.

  13. fundic glands location：lamina propria compositions： 1.Chief C 2.Parietal C 3.Neck mucous C 4.Endocrine C 5.Stem C

  14. Secretory granule nucleus rER Chief cells • LM: • Lower columnar; • basophilic; • Nucleus located in the lower parts. • Secretory granules. • EM: • Gol , Apical of the nucleus; • mit. & rER ,basal part of cytoplasm; • Secretory granules, apical ofcytoplasm. • Function :pepsinogen

  15. microvilli nucleus Introcellular canaliculi Mitochondria Parietal cells • LM: • C large，cone-shapedor round. • acidophilic. • Nucleus is round ,centrical. • EM • Introcellular secretory canaliculi & microvilli. • Tubulovesicular system. • Mit. are abundant. • functions: • Hcl & intrinsic factor.

  16. small intestine ileum jejunum duodenum

  17. 1 striated border Central lacteal 1 absorbtive C 2 goblet C SMC Cap. 5 stem C Intestinal gland 3 Paneth C 4 endocrine C

  18. villi folds submucosa muscularis adventitia Intestinal villi

  19. microvilli （striated border）

  20. Small intestine • mucosa: • Epi.: simple columnar, absorbtive C + gobletC. • Lamina propria: small intestinal gland ,central lacteal. • Muscularis mucosa: inner circular, outer longitudinal. villi: the finger-like processes composed of epithelium layer and lamina propria protruding into the lumen .

  21. submucosa • The duodenal gland, mucosa. Circular folds: mucosa&submucosa protruding into the lumen . Appears as processes. • muscularis: inner circular,outer longitudinal . • adventitia: serosa.

  22. @@@@@small intestinal gland • AbsorbtiveC • GobletC • EndocrineC • StemC • Paneth C • LM: the base of gland. arranged in groups of 3-5 cells . in the apex, coarse acidophilic granules. • EM: protein-secreting cell. • functions: produce lysozyme.

  23. Large intestinal

  24. Epi. Large intestinal gland （goblet C） Lamina propria Muscularis mucosa Mucosa of large intestine（HE）

  25. Large intestine • mucosa: no villi ,no circular folds. • Simple columnar Epi.: abundant goblet C. • Lamina propria: large intestinal glands, no paneth C. • Muscularis mucosa:

  26. appendix • No villi, • intestinal gland • Is scanty. • Lamina propria: • abundant LT. • Serosa

  27. The comparisons between mucosa of variant digestive tract （1） Small intestine Large intestine esophagus stomach Gastric pit surface villus Simple columnar Striated border Goblet C Simple Columnar Goblet C abundant Striated squamous Simple columnar Epi.

  28. The comparisons between mucosa of variant digestive tract （2） • Fundic gland of stomach: chief , parietal, neck mucous , endocrine, stem C. • Small intestinal gland: absorbtive, goblet, paneth, endocrine, stem C. • Large intestinal gland: absorbtive, goblet, endocrine, stem C.

  29. Key points • Structure characteristics of variant digestive tract. The similar and the different. • Esp, the variance of tunica mucosa. Such as , the villi and the glands.

  30. Thank you !

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