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Pasca_Supplemental Figure 3. v. n. A. B. C. control. Pdx-Cre;CLEG2. Pdx-Cre;CLEG2;Kras G12D. s. s. s. d. p. d. p. p. d. control. CT. CKAT. CKP. CNP. CT : C LEG T umors - in 30% of the animals - anaplastic histology. CKAT : C LEG; K ras A naplastic T umors

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  1. Pasca_Supplemental Figure 3 v n A B C control Pdx-Cre;CLEG2 Pdx-Cre;CLEG2;KrasG12D s s s d p d p p d control CT CKAT CKP CNP CT: CLEG Tumors - in 30% of the animals - anaplastic histology. CKAT: CLEG;Kras Anaplastic Tumors are observed in ~60% of the animals Tumors are highly vascularized and reach significant sizes. Mostly observed in animals that survive longer than 6 weeks. CKP: CLEG;Kras PanIN lesions, surrounded by stroma have replaced all of the normal pancreatic tissue. CNP: CLEG Normal Pancreas constitutes the majority of the pancreatic tissue.

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