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Radiographic Changes in Brain Melanoma Metastases Post-CTLA-4 Blockade Treatment

This study by Hodi et al. (2008) explores the radiographic changes observed in a female patient with melanoma metastases in the CNS following CTLA-4 blockade using ipilimumab. The research highlights the significant clinical benefits of CTLA-4 blockade treatment in managing brain metastases, demonstrating its potential effectiveness for patients with metastatic melanoma. Enhanced understanding of tumor responses to immunotherapy can guide future treatment strategies and improve patient outcomes in similar cases.

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Radiographic Changes in Brain Melanoma Metastases Post-CTLA-4 Blockade Treatment

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  1. Figure 1 Radiographic changes to melanoma metastases in the brain with administration of CTLA-4 blockade Hodi FS et al. (2008) CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS Nat Clin Pract Oncol doi:10.1038/ncponc1183

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