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B-lymphocytes (CD19+)

A). B-lymphocytes (CD19+). 3. 2. cell/ml of blood (x10 6 ). 1. 0. 5. 10. 15. 20. 25. rAAV5- pbgd. rAAV5- egfp. rAAV5- pbgd. rAAV5- egfp. Weeks. rAAV5- pbgd. rAAV5- egfp. NHP001 w/o IS. B). NHP002 with IS. CD4 + T cells. NHP003 with IS. 2.5. 2.0. 1.5.

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B-lymphocytes (CD19+)

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  1. A) B-lymphocytes (CD19+) 3 2 cell/ml of blood (x106) 1 0 5 10 15 20 25 rAAV5- pbgd rAAV5- egfp rAAV5- pbgd rAAV5- egfp Weeks rAAV5- pbgd rAAV5- egfp NHP001 w/o IS B) NHP002 with IS CD4+ T cells NHP003 with IS 2.5 2.0 1.5 cell/ml of blood (x106) 1.0 0.5 0 5 10 15 20 25 Weeks C) CD8+ T cells 2.0 1.5 cell/ml of blood (x106) 1.0 0.5 0 5 10 15 20 25 Weeks

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